2-Amino-5-fluorobenzoic acid

Base Information

Chemical Name:2-Amino-5-fluorobenzoic acid
CAS No.:446-08-2
Molecular Formula:C7H6FNO2
Molecular Weight:155.129
Hs Code.:29224999
European Community (EC) Number:207-159-7
NSC Number:513308
UNII:5VD9746EAR
DSSTox Substance ID:DTXSID60196231
Nikkaji Number:J196.138A
Wikidata:Q27147609
ChEMBL ID:CHEMBL4585642
Mol file:446-08-2.mol

Synonyms:2-amino-5-fluorobenzoic acid;5-FABA cpd

Suppliers and Price of 2-Amino-5-fluorobenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
5-Fluoroanthranilic Acid
250mg
$ 134.00

TRC
5-Fluoroanthranilic Acid
1g
$ 70.00

TRC
5-Fluoroanthranilic Acid
250mg
$ 65.00

TCI Chemical
5-Fluoroanthranilic Acid >98.0%(HPLC)(T)
5g
$ 165.00

TCI Chemical
5-Fluoroanthranilic Acid >98.0%(HPLC)(T)
1g
$ 42.00

SynQuest Laboratories
2-Amino-5-fluorobenzoic acid 98%
100 g
$ 131.00

SynQuest Laboratories
2-Amino-5-fluorobenzoic acid 98%
5 g
$ 21.00

Sigma-Aldrich
2-Amino-5-fluorobenzoic acid 97%
1g
$ 60.50

Sigma-Aldrich
2-Amino-5-fluorobenzoic acid 97%
10g
$ 369.00

Medical Isotopes, Inc.
2-Amino-5-fluorobenzoic acid
10 g
$ 1760.00

Total 154 raw suppliers

Chemical Property of 2-Amino-5-fluorobenzoic acid

Chemical Property:

Appearance/Colour:white to light yellow crystal powder
Vapor Pressure:0.000154mmHg at 25°C
Melting Point:181-183 °C(lit.)
Boiling Point:318.2 °C at 760 mmHg
PKA:1.86±0.10(Predicted)
Flash Point:146.2 °C
PSA：63.32000
Density:1.43 g/cm³
LogP:1.68730
Storage Temp.:Room temperature.
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:155.03825660
Heavy Atom Count:11
Complexity:163

Purity/Quality:

98% ^*data from raw suppliers

5-Fluoroanthranilic Acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi, T
Hazard Codes:Xi,T
Statements: 36/37/38
Safety Statements: 26-36-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1F)C(=O)O)N
Uses 2-Amino-5-fluorobenzoic acid is used for the counterselection of TRP1, a commonly used genetic marker in the yeast Saccharoyces Cerevisiae. An antimetabolite for the tryptophan pathway in yeast, and is toxic by virtue of its antimetabolite conversion to 5-Fluorotryptophan. It can be used for the selection of tryptophan auxotroophs. Used in the synthesis of styrylquinazolinones which are potential anticancer agents.

Technology Process of 2-Amino-5-fluorobenzoic acid

There total 12 articles about 2-Amino-5-fluorobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%