(S)-methyl 2-(1-(((benzyloxy)carbonyl)amino)ethyl)-3-(pyridin-3-yl)imidazo[1,2-a]pyridine-5-carboxylate ester

Base Information

Chemical Name:(S)-methyl 2-(1-(((benzyloxy)carbonyl)amino)ethyl)-3-(pyridin-3-yl)imidazo[1,2-a]pyridine-5-carboxylate ester
CAS No.:1338484-96-0
Molecular Formula:C₂₄H₂₂N₄O₄
Molecular Weight:430.463
Hs Code.:

Synonyms:(S)-methyl 2-(1-(((benzyloxy)carbonyl)amino)ethyl)-3-(pyridin-3-yl)imidazo[1,2-a]pyridine-5-carboxylate ester

Suppliers and Price of (S)-methyl 2-(1-(((benzyloxy)carbonyl)amino)ethyl)-3-(pyridin-3-yl)imidazo[1,2-a]pyridine-5-carboxylate ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-methyl 2-(1-(((benzyloxy)carbonyl)amino)ethyl)-3-(pyridin-3-yl)imidazo[1,2-a]pyridine-5-carboxylate ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-methyl 2-(1-(((benzyloxy)carbonyl)amino)ethyl)-3-(pyridin-3-yl)imidazo[1,2-a]pyridine-5-carboxylate ester

There total 5 articles about (S)-methyl 2-(1-(((benzyloxy)carbonyl)amino)ethyl)-3-(pyridin-3-yl)imidazo[1,2-a]pyridine-5-carboxylate ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1338484-24-4
(S)-methyl 2-(1-(benzyloxycarbonylamino)ethyl)-3-iodoimidazo[1,2-a]pyridine-5-carboxylate

: 1692-25-7
3-pyridylboronic acid

: 1338484-96-0
(S)-methyl 2-(1-(((benzyloxy)carbonyl)amino)ethyl)-3-(pyridin-3-yl)imidazo[1,2-a]pyridine-5-carboxylate ester

Guidance literature:: With sodium carbonate; bis-triphenylphosphine-palladium(II) chloride; In ethanol; water; toluene; at 25 - 120 ℃; Inert atmosphere;

Reference yield:

: 1142-20-7
N-Cbz-Ala

: 1338484-96-0
(S)-methyl 2-(1-(((benzyloxy)carbonyl)amino)ethyl)-3-(pyridin-3-yl)imidazo[1,2-a]pyridine-5-carboxylate ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: 4-methyl-morpholine; isobutyl chloroformate / tetrahydrofuran / 1.5 h / -20 °C

1.2: -20 - 20 °C

1.3: 0.5 h / 0 °C

2.1: ethanol / Reflux

3.1: N-iodo-succinimide / acetonitrile / 25 °C

4.1: sodium carbonate / bis-triphenylphosphine-palladium(II) chloride / toluene; ethanol; water / 25 - 120 °C / Inert atmosphere

With 4-methyl-morpholine; N-iodo-succinimide; sodium carbonate; isobutyl chloroformate; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; ethanol; water; toluene; acetonitrile;

Reference yield:

: 36052-26-3
methyl 6-aminopyridine-2-carboxylate

: 1338484-96-0
(S)-methyl 2-(1-(((benzyloxy)carbonyl)amino)ethyl)-3-(pyridin-3-yl)imidazo[1,2-a]pyridine-5-carboxylate ester

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol / Reflux

2: N-iodo-succinimide / acetonitrile / 25 °C

3: sodium carbonate / bis-triphenylphosphine-palladium(II) chloride / toluene; ethanol; water / 25 - 120 °C / Inert atmosphere

With N-iodo-succinimide; sodium carbonate; bis-triphenylphosphine-palladium(II) chloride; In ethanol; water; toluene; acetonitrile;