4,5,6,7,8,9,10,11,12,13-decahydro-3-iodo-2-phenylcyclododeca[b]furan

Base Information

• Chemical Name: 4,5,6,7,8,9,10,11,12,13-decahydro-3-iodo-2-phenylcyclododeca[b]furan
• CAS No.: 1032196-70-5
• Molecular Formula: C₂₀H₂₅IO
• Molecular Weight: 408.322
• Mol file: 1032196-70-5.mol

Synonyms:4,5,6,7,8,9,10,11,12,13-decahydro-3-iodo-2-phenylcyclododeca[b]furan

Chemical Property of 4,5,6,7,8,9,10,11,12,13-decahydro-3-iodo-2-phenylcyclododeca[b]furan

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,5,6,7,8,9,10,11,12,13-decahydro-3-iodo-2-phenylcyclododeca[b]furan

There total 1 articles about 4,5,6,7,8,9,10,11,12,13-decahydro-3-iodo-2-phenylcyclododeca[b]furan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

1-(2-phenylethynyl)-13-oxabicyclo[10.1.0]tridecane (1032196-46-5) → 4,5,6,7,8,9,10,11,12,13-decahydro-3-iodo-2-phenylcyclododeca[b]furan (1032196-70-5)

Guidance literature:

With iodine; sodium hydrogencarbonate; In tetrahydrofuran; at 20 ℃; for 2h;

DOI:10.1002/ejoc.200700963

Reference yield: 59.0%

4,5,6,7,8,9,10,11,12,13-decahydro-3-iodo-2-phenylcyclododeca[b]furan (1032196-70-5) + phenylboronic acid (98-80-6) → 4,5,6,7,8,9,10,11,12,13-decahydro-2,3-diphenylcyclododeca[b]furan (1032196-79-4)

Guidance literature:

With palladium diacetate; potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 6h;

DOI:10.1002/ejoc.200700963

Reference yield: 38.0%

4,5,6,7,8,9,10,11,12,13-decahydro-3-iodo-2-phenylcyclododeca[b]furan (1032196-70-5) + 2-Allyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (72824-04-5) → C23H30O

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; cesium fluoride; In tetrahydrofuran; for 12h; Inert atmosphere; Reflux;

DOI:10.1002/ejoc.201901613

upstream raw materials:

1-(2-phenylethynyl)-13-oxabicyclo[10.1.0]tridecane

Downstream raw materials:

4,5,6,7,8,9,10,11,12,13-decahydro-2,3-diphenylcyclododeca[b]furan