N-[1-(N-glycine ethyl ester)-1-oxo-3-(1-methylindol-3-yl)prop-2-en-2-yl]benzamide

Base Information

Chemical Name:N-[1-(N-glycine ethyl ester)-1-oxo-3-(1-methylindol-3-yl)prop-2-en-2-yl]benzamide
CAS No.:257880-58-3
Molecular Formula:C₂₃H₂₃N₃O₄
Molecular Weight:405.453
Hs Code.:

Synonyms:N-[1-(N-glycine ethyl ester)-1-oxo-3-(1-methylindol-3-yl)prop-2-en-2-yl]benzamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[1-(N-glycine ethyl ester)-1-oxo-3-(1-methylindol-3-yl)prop-2-en-2-yl]benzamide

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Technology Process of N-[1-(N-glycine ethyl ester)-1-oxo-3-(1-methylindol-3-yl)prop-2-en-2-yl]benzamide

There total 3 articles about N-[1-(N-glycine ethyl ester)-1-oxo-3-(1-methylindol-3-yl)prop-2-en-2-yl]benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 623-33-6
glycine ethyl ester hydrochloride

: 257880-47-0
2-phenyl-4-[(1-methylindol-3-yl)methylene]-1,3-oxazol-5(4H)-one

: 257880-58-3
N-[1-(N-glycine ethyl ester)-1-oxo-3-(1-methylindol-3-yl)prop-2-en-2-yl]benzamide

Guidance literature:: With triethylamine; In tetrahydrofuran; at 0 ℃; for 0.5h;

Reference yield:

: 495-69-2,140480-84-8,21251-67-2,91787-63-2,66407-11-2
Hippuric Acid

: 257880-58-3
N-[1-(N-glycine ethyl ester)-1-oxo-3-(1-methylindol-3-yl)prop-2-en-2-yl]benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: NaOAc; Ac₂O / 3 h / 100 °C

2: Et₃N / tetrahydrofuran / 0.5 h / 0 °C

With sodium acetate; acetic anhydride; triethylamine; In tetrahydrofuran; 1: Condensation / 2: Condensation;

Reference yield:

: 19012-03-4
N-methyl-3-formylindole

: 257880-58-3
N-[1-(N-glycine ethyl ester)-1-oxo-3-(1-methylindol-3-yl)prop-2-en-2-yl]benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: NaOAc; Ac₂O / 3 h / 100 °C

2: Et₃N / tetrahydrofuran / 0.5 h / 0 °C

With sodium acetate; acetic anhydride; triethylamine; In tetrahydrofuran; 1: Condensation / 2: Condensation;