N'-[(E)-(4-oxo-4H-chromen-3-yl)methylidene]benzenecarbohydrazide

Base Information

Chemical Name:N'-[(E)-(4-oxo-4H-chromen-3-yl)methylidene]benzenecarbohydrazide
CAS No.:902779-63-9
Molecular Formula:C₁₇H₁₂N₂O₃
Molecular Weight:292.294
Hs Code.:
DSSTox Substance ID:DTXSID101331827
ChEMBL ID:CHEMBL1241822
Mol file:902779-63-9.mol

Synonyms:902779-63-9;CHEMBL1241822;N'-[(E)-(4-oxo-4H-chromen-3-yl)methylidene]benzenecarbohydrazide;N-[(E)-(4-oxochromen-3-yl)methylideneamino]benzamide;N'-[(1E)-(4-oxo-4H-chromen-3-yl)methylidene]benzohydrazide;MLS000763907;SCHEMBL3342977;DTXSID101331827;BDBM50326128;AKOS005094610;SMR000336524;5W-0284;N''-((4-oxo-4H-chromen-3-yl)methylene)benzohydrazide

Suppliers and Price of N'-[(E)-(4-oxo-4H-chromen-3-yl)methylidene]benzenecarbohydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N'-[(E)-(4-OXO-4H-CHROMEN-3-YL)METHYLIDENE]BENZENECARBOHYDRAZIDE 95.00%
5MG
$ 687.35

American Custom Chemicals Corporation
N'-[(E)-(4-OXO-4H-CHROMEN-3-YL)METHYLIDENE]BENZENECARBOHYDRAZIDE 95.00%
10MG
$ 679.14

American Custom Chemicals Corporation
N'-[(E)-(4-OXO-4H-CHROMEN-3-YL)METHYLIDENE]BENZENECARBOHYDRAZIDE 95.00%
1MG
$ 647.61

Total 1 raw suppliers

Chemical Property of N'-[(E)-(4-oxo-4H-chromen-3-yl)methylidene]benzenecarbohydrazide

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:292.08479225
Heavy Atom Count:22
Complexity:492

Purity/Quality:: N'-[(E)-(4-OXO-4H-CHROMEN-3-YL)METHYLIDENE]BENZENECARBOHYDRAZIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)NN=CC2=COC3=CC=CC=C3C2=O
Isomeric SMILES:C1=CC=C(C=C1)C(=O)N/N=C/C2=COC3=CC=CC=C3C2=O

Technology Process of N'-[(E)-(4-oxo-4H-chromen-3-yl)methylidene]benzenecarbohydrazide

There total 3 articles about N'-[(E)-(4-oxo-4H-chromen-3-yl)methylidene]benzenecarbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 902779-63-9
(E)-N'-((4-oxo-4H-chromen-3-yl)methylene)benzohydrazide

Guidance literature:: In ethanol; at 40 ℃;

Reference yield: 68.4%

: 613-94-5
benzoic acid hydrazide

: 17422-74-1
3-Formylchromone

: 902779-63-9
(E)-N'-((4-oxo-4H-chromen-3-yl)methylene)benzohydrazide

Guidance literature:: With acetic acid; In ethanol; for 6h; Reflux;
DOI:10.1016/j.bmcl.2017.05.007

Reference yield:

: 118-93-4,104809-67-8
o-hydroxyacetophenone

: 902779-63-9
(E)-N'-((4-oxo-4H-chromen-3-yl)methylene)benzohydrazide

Guidance literature:: Multi-step reaction with 2 steps

1.1: trichlorophosphate / 2 h / 50 °C

1.2: 2 h / 50 °C

2.1: acetic acid / ethanol / 6 h / Reflux

With acetic acid; trichlorophosphate; In ethanol; 1.1: |Vilsmeier-Haack Formylation / 1.2: |Vilsmeier-Haack Formylation;
DOI:10.1016/j.bmcl.2017.05.007