C₁₀H₁₆OSi

Base Information

• Chemical Name: C₁₀H₁₆OSi
• CAS No.: 1443366-07-1
• Molecular Formula: C₁₀H₁₆OSi
• Molecular Weight: 180.322
• Mol file: 1443366-07-1.mol

Synonyms:C₁₀H₁₆OSi

Chemical Property of C₁₀H₁₆OSi

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₁₀H₁₆OSi

There total 1 articles about C₁₀H₁₆OSi which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

C10H15BrOSi (1443366-06-0) → C10H16OSi (1443366-07-1)

Guidance literature:

With n-butyllithium; In diethyl ether; at -78 - 20 ℃; for 23h;

DOI:10.1002/adsc.201200703

Reference yield:

C10H16OSi (1443366-07-1) → 9-hexyl-8-methyl-1-tosyl-2,3,4,9-tetrahydro-1H-benzo[f]indole (1443365-96-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: diethyl ether / -78 °C

1.2: 3 h / -78 - 20 °C

2.1: cesium fluoride / toluene; acetonitrile / 21 h / 20 °C / Inert atmosphere; Glovebox

With cesium fluoride; In diethyl ether; toluene; acetonitrile; 2.1: |Diels-Alder Cycloaddition;

DOI:10.1002/adsc.201200703

Reference yield:

n-butyllithium (109-72-8,29786-93-4) + trifluoromethylsulfonic anhydride (358-23-6) + C10H16OSi (1443366-07-1) → 2-methyl-6-(trimethylsilyl)phenyl trifluoromethanesulfonate (556812-44-3)

Guidance literature:

n-butyllithium; C₁₀H₁₆OSi; In diethyl ether; at -78 ℃;

trifluoromethylsulfonic anhydride; at -78 - 20 ℃; for 3h;

DOI:10.1002/adsc.201200703

upstream raw materials:

C₁₀H₁₅BrOSi

Downstream raw materials:

9-hexyl-8-methyl-1-tosyl-2,3,4,9-tetrahydro-1H-benzo[f]indole

2-methyl-6-(trimethylsilyl)phenyl trifluoromethanesulfonate