N-<3-(tert-butoxycarbonyl)-N--L-alanyl>-3-phenyl-L-alanine tert-butyl ester

Base Information

• Chemical Name: N-<3-(tert-butoxycarbonyl)-N--L-alanyl>-3-phenyl-L-alanine tert-butyl ester
• CAS No.: 144411-97-2
• Molecular Formula: C₃₁H₃₈N₄O₇
• Molecular Weight: 578.665

Synonyms:N-<3-(tert-butoxycarbonyl)-N--L-alanyl>-3-phenyl-L-alanine tert-butyl ester

Chemical Property of N-<3-(tert-butoxycarbonyl)-N--L-alanyl>-3-phenyl-L-alanine tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-<3-(tert-butoxycarbonyl)-N--L-alanyl>-3-phenyl-L-alanine tert-butyl ester

There total 2 articles about N-<3-(tert-butoxycarbonyl)-N--L-alanyl>-3-phenyl-L-alanine tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-3-(2-Benzyloxycarbonylamino-acetylamino)-N-((S)-1-tert-butoxycarbonyl-2-phenyl-ethyl)-succinamic acid tert-butyl ester → N-<3-(tert-butoxycarbonyl)-N--L-alanyl>-3-phenyl-L-alanine tert-butyl ester (144411-97-2)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / Pd/C / ethanol

2: O-benzotriazol-1-yl-N,N,N',N'-tetramethyluronium hexafluorophosphate (HBTU), N-methylmorpholine (NMM) / tetrahydrofuran / 6 h / Ambient temperature

With 4-methyl-morpholine; hydrogen; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; palladium on activated charcoal; In tetrahydrofuran; ethanol;

DOI:10.1021/jm00101a017

Reference yield:

4-cyanobenzoic Acid (619-65-8,333406-09-0) + H-Gly-Asp(O-t-Bu)-Phe-O-t-Bu (131668-91-2) → N-<3-(tert-butoxycarbonyl)-N--L-alanyl>-3-phenyl-L-alanine tert-butyl ester (144411-97-2)

Guidance literature:

With 4-methyl-morpholine; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; In tetrahydrofuran; for 6h; Ambient temperature;

DOI:10.1021/jm00101a017

Reference yield:

N-<3-(tert-butoxycarbonyl)-N--L-alanyl>-3-phenyl-L-alanine tert-butyl ester (144411-97-2) → (S)-N-((S)-1-tert-Butoxycarbonyl-2-phenyl-ethyl)-3-[2-(4-thiocarbamoyl-benzoylamino)-acetylamino]-succinamic acid tert-butyl ester (1025822-82-5)

Guidance literature:

With hydrogen sulfide; triethylamine; In pyridine; Ambient temperature;

DOI:10.1021/jm00101a017

upstream raw materials:

4-cyanobenzoic Acid

H-Gly-Asp(O-t-Bu)-Phe-O-t-Bu

Downstream raw materials:

(S)-N-((S)-1-tert-Butoxycarbonyl-2-phenyl-ethyl)-3-[2-(4-thiocarbamoyl-benzoylamino)-acetylamino]-succinamic acid tert-butyl ester

(S)-2-{(S)-3-tert-Butoxycarbonyl-2-[4-(4-cyano-benzoylamino)-butyrylamino]-propionylamino}-3-methyl-butyric acid tert-butyl ester

(S)-2-{(S)-3-tert-Butoxycarbonyl-2-[4-(4-carbamimidoyl-benzoylamino)-butyrylamino]-propionylamino}-3-methyl-butyric acid tert-butyl ester

(S)-2-{(S)-3-tert-Butoxycarbonyl-2-[4-(4-thiocarbamoyl-benzoylamino)-butyrylamino]-propionylamino}-3-methyl-butyric acid tert-butyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 144411-97-2 N-<3-(tert-butoxycarbonyl)-N--L-alanyl>-3-phenyl-L-alanine tert-butyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send