1-benzyl-2,3-diethyl-4,5,6-trimethyl-1,2-dihydropyridine

Base Information

• Chemical Name: 1-benzyl-2,3-diethyl-4,5,6-trimethyl-1,2-dihydropyridine
• CAS No.: 1016970-61-8
• Molecular Formula: C₁₉H₂₇N
• Molecular Weight: 269.43
• Mol file: 1016970-61-8.mol

Synonyms:1-benzyl-2,3-diethyl-4,5,6-trimethyl-1,2-dihydropyridine

Chemical Property of 1-benzyl-2,3-diethyl-4,5,6-trimethyl-1,2-dihydropyridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-benzyl-2,3-diethyl-4,5,6-trimethyl-1,2-dihydropyridine

There total 2 articles about 1-benzyl-2,3-diethyl-4,5,6-trimethyl-1,2-dihydropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

hex-3-yne (928-49-4) + (2E,3E)-N-benzyl-3-methylpent-3-en-2-imine → 1-benzyl-2,3-diethyl-4,5,6-trimethyl-1,2-dihydropyridine (1016970-61-8)

Guidance literature:

[RhCl(coe)2]2; In toluene; at 100 ℃; for 2h;

DOI:10.1021/ja7104784

Reference yield:

hex-3-yne (928-49-4) + C13H17N (1016970-52-7) → 1-benzyl-2,3-diethyl-4,5,6-trimethyl-1,2-dihydropyridine (1016970-61-8)

Guidance literature:

With [RhCl(cis-cyclooctene)2]2; diethyl-{4-dimethylamino-phenyl}-phosphine; In toluene; at 80 ℃; for 1h; regioselective reaction; Inert atmosphere;

DOI:10.1021/ja2119833

Reference yield: 89.0%

1-benzyl-2,3-diethyl-4,5,6-trimethyl-1,2-dihydropyridine (1016970-61-8) + acrylic acid methyl ester (292638-85-8,9003-21-8,96-33-3) → C23H33NO2

Guidance literature:

In neat (no solvent); at 105 ℃; for 16h; diastereoselective reaction; Inert atmosphere; Glovebox;

DOI:10.1021/ol303040r

upstream raw materials:

hex-3-yne

C₁₃H₁₇N