3,4,5,7-Tetra-O-benzyl-2,6-anhydro-1-deoxy-D-glycero-D-gulo-heptitol

Base Information

• Chemical Name: 3,4,5,7-Tetra-O-benzyl-2,6-anhydro-1-deoxy-D-glycero-D-gulo-heptitol
• CAS No.: 95189-55-2
• Molecular Formula: C₃₅H₃₈O₅
• Molecular Weight: 538.684
• Mol file: 95189-55-2.mol

Synonyms:3,4,5,7-Tetra-O-benzyl-2,6-anhydro-1-deoxy-D-glycero-D-gulo-heptitol

Chemical Property of 3,4,5,7-Tetra-O-benzyl-2,6-anhydro-1-deoxy-D-glycero-D-gulo-heptitol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4,5,7-Tetra-O-benzyl-2,6-anhydro-1-deoxy-D-glycero-D-gulo-heptitol

There total 13 articles about 3,4,5,7-Tetra-O-benzyl-2,6-anhydro-1-deoxy-D-glycero-D-gulo-heptitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

3,4,5,7-Tetra-O-benzyl-1-deoxy-D-gluco-2-heptulopyranose (137344-41-3,138811-37-7,138811-38-8,140849-70-3) → 3,4,5,7-Tetra-O-benzyl-2,6-anhydro-1-deoxy-D-glycero-D-gulo-heptitol (95189-55-2)

Guidance literature:

With triethylsilane; trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at -78 ℃; for 1h;

DOI:10.1021/ol048525+

Reference yield: 80.0%

dimethyl zinc(II) (544-97-8) + phenyl 2,3,4,6-tetra-O-benzyl-1-thio-β-D-mannopyranoside (187226-51-3) → (2,3,4,6-tetra-O-benzyl-D-mannopyranosyl)-methane α,β anomers (4132-32-5,95189-55-2,116501-54-3,116501-55-4)

Guidance literature:

With diiodomethane; In toluene; at 40 ℃; for 3h;

DOI:10.1016/S0008-6215(00)90882-6

Reference yield: 80.0%

2,6-anhydro-3,4,5,7-tetra-O-benzyl-1-deoxy-1,1-dichloro-D-gluco-hept-1-enitol (136742-92-2) → 3,4,5,7-Tetra-O-benzyl-2,6-anhydro-1-deoxy-D-glycero-D-gulo-heptitol (95189-55-2)

Guidance literature:

With hydrogen; nickel; In ethyl acetate;

DOI:10.1039/P19920001471

upstream raw materials:

phenyl 2,3,4,5-tetra-O-benzyl-1-thio-β-D-glucopyranoside

dimethyl zinc(II)

phenyl 2,3,4,6-tetra-O-acetyl-1-thio-α-D-glucopyranoside

butyl 2,3,4,6-tetra-O-benzyl-1-thio-β-D-glucopyranoside