allyl O-(2,3-di-O-benzyl-α-D-galactopyranosyl)-(1->4)-O-(6-O-acetyl-2,3-di-O-benzyl-α-D-galactopyranosyl)-(1->4)-6-O-acetyl-2,3-di-O-benzyl-β-D-galactopyranoside

Base Information

• Chemical Name: allyl O-(2,3-di-O-benzyl-α-D-galactopyranosyl)-(1->4)-O-(6-O-acetyl-2,3-di-O-benzyl-α-D-galactopyranosyl)-(1->4)-6-O-acetyl-2,3-di-O-benzyl-β-D-galactopyranoside
• CAS No.: 113765-33-6
• Molecular Formula: C₆₇H₇₆O₁₈
• Molecular Weight: 1169.33
• Mol file: 113765-33-6.mol

Synonyms:allyl O-(2,3-di-O-benzyl-α-D-galactopyranosyl)-(1->4)-O-(6-O-acetyl-2,3-di-O-benzyl-α-D-galactopyranosyl)-(1->4)-6-O-acetyl-2,3-di-O-benzyl-β-D-galactopyranoside

Chemical Property of allyl O-(2,3-di-O-benzyl-α-D-galactopyranosyl)-(1->4)-O-(6-O-acetyl-2,3-di-O-benzyl-α-D-galactopyranosyl)-(1->4)-6-O-acetyl-2,3-di-O-benzyl-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of allyl O-(2,3-di-O-benzyl-α-D-galactopyranosyl)-(1->4)-O-(6-O-acetyl-2,3-di-O-benzyl-α-D-galactopyranosyl)-(1->4)-6-O-acetyl-2,3-di-O-benzyl-β-D-galactopyranoside

There total 10 articles about allyl O-(2,3-di-O-benzyl-α-D-galactopyranosyl)-(1->4)-O-(6-O-acetyl-2,3-di-O-benzyl-α-D-galactopyranosyl)-(1->4)-6-O-acetyl-2,3-di-O-benzyl-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

allyl 6-O-acetyl-2,3-di-O-benzyl-β-D-galactopyranoside (113765-20-1) → allyl O-(2,3-di-O-benzyl-α-D-galactopyranosyl)-(1->4)-O-(6-O-acetyl-2,3-di-O-benzyl-α-D-galactopyranosyl)-(1->4)-6-O-acetyl-2,3-di-O-benzyl-β-D-galactopyranoside (113765-33-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 74.1 percent / SnCl₂, AgClO₄, molecular sieves 4A / diethyl ether; toluene / 20 h / -15 deg C to rt

2: 89.8 percent / pyridine / 1.5 h / 0 °C

3: 170 mg / SnCl₂, AgClO₄, molecular sieves 4A / diethyl ether; toluene / 6 h / -15 - -5 °C

4: 138 mg / 80 percent aq. AcOH / 0.5 h / 60 °C

With 4 A molecular sieve; silver perchlorate; acetic acid; tin(ll) chloride; In pyridine; diethyl ether; toluene;

DOI:10.1016/0008-6215(89)85010-4

Reference yield:

2,3-di-O-benzyl-4,6-O-isopropylidene-D-galactopyranose (117780-23-1) → allyl O-(2,3-di-O-benzyl-α-D-galactopyranosyl)-(1->4)-O-(6-O-acetyl-2,3-di-O-benzyl-α-D-galactopyranosyl)-(1->4)-6-O-acetyl-2,3-di-O-benzyl-β-D-galactopyranoside (113765-33-6)

Guidance literature:

Multi-step reaction with 5 steps

1: 37.8 percent / diethylaminosulfur trifluoride / tetrahydrofuran / 0.5 h / Ambient temperature

2: 74.1 percent / SnCl₂, AgClO₄, molecular sieves 4A / diethyl ether; toluene / 20 h / -15 deg C to rt

3: 89.8 percent / pyridine / 1.5 h / 0 °C

4: 170 mg / SnCl₂, AgClO₄, molecular sieves 4A / diethyl ether; toluene / 6 h / -15 - -5 °C

5: 138 mg / 80 percent aq. AcOH / 0.5 h / 60 °C

With diethylamino-sulfur trifluoride; 4 A molecular sieve; silver perchlorate; acetic acid; tin(ll) chloride; In tetrahydrofuran; pyridine; diethyl ether; toluene;

DOI:10.1016/0008-6215(89)85010-4

Reference yield:

allyl 2,3-di-Ο-benzyl-β-D-galactopyranoside (97817-99-7) → allyl O-(2,3-di-O-benzyl-α-D-galactopyranosyl)-(1->4)-O-(6-O-acetyl-2,3-di-O-benzyl-α-D-galactopyranosyl)-(1->4)-6-O-acetyl-2,3-di-O-benzyl-β-D-galactopyranoside (113765-33-6)

Guidance literature:

Multi-step reaction with 5 steps

1: 77.8 percent / pyridine / 2 h / Ambient temperature

2: 74.1 percent / SnCl₂, AgClO₄, molecular sieves 4A / diethyl ether; toluene / 20 h / -15 deg C to rt

3: 89.8 percent / pyridine / 1.5 h / 0 °C

4: 170 mg / SnCl₂, AgClO₄, molecular sieves 4A / diethyl ether; toluene / 6 h / -15 - -5 °C

5: 138 mg / 80 percent aq. AcOH / 0.5 h / 60 °C

With 4 A molecular sieve; silver perchlorate; acetic acid; tin(ll) chloride; In pyridine; diethyl ether; toluene;

DOI:10.1016/0008-6215(89)85010-4

upstream raw materials:

C₇₀H₈₀O₁₈

2,3-di-O-benzyl-4,6-O-isopropylidene-D-galactopyranose

allyl 2,3-di-Ο-benzyl-β-D-galactopyranoside

allyl 6-O-acetyl-2,3-di-O-benzyl-β-D-galactopyranoside

Downstream raw materials:

allyl O-(6-O-acetyl-2,3-di-O-benzyl-α-D-galactopyranosyl)-(1->4)-O-(6-O-acetyl-2,3-di-O-benzyl-α-D-galactopyranosyl)-(1->4)-6-O-acetyl-2,3-di-O-benzyl-β-D-galactopyranoside