2-Chloro-5,6-dimethyl-3-nitropyridine

Base Information

Chemical Name:2-Chloro-5,6-dimethyl-3-nitropyridine
CAS No.:65213-96-9
Molecular Formula:C7H7 Cl N2 O2
Molecular Weight:186.59568
Hs Code.:2933399090
DSSTox Substance ID:DTXSID60435258
Mol file:65213-96-9.mol

Synonyms:2-chloro-5,6-dimethyl-3-nitropyridine;65213-96-9;2-chloro-5,6-dimethyl-3-nitro-pyridine;SCHEMBL217060;DTXSID60435258;PLOHNISKTBOURT-UHFFFAOYSA-N;AKOS006332283;AKOS015967412;FT-0709661

Suppliers and Price of 2-Chloro-5,6-dimethyl-3-nitropyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-CHLORO-5,6-DIMETHYL-3-NITRO-PYRIDINE 95.00%
5MG
$ 500.39

Total 5 raw suppliers

Chemical Property of 2-Chloro-5,6-dimethyl-3-nitropyridine

Chemical Property:

PSA：58.71000
LogP:2.78320
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:186.0196052
Heavy Atom Count:12
Complexity:183

Purity/Quality:

95% ^*data from raw suppliers

2-CHLORO-5,6-DIMETHYL-3-NITRO-PYRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=C(N=C1C)Cl)[N+](=O)[O-]

Technology Process of 2-Chloro-5,6-dimethyl-3-nitropyridine

There total 6 articles about 2-Chloro-5,6-dimethyl-3-nitropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 98276-88-1
3-nitro-5,6-dimethyl-2(1H)-pyridinone

: 65213-96-9
2,3-dimethyl-6-chloro-5-nitropyridine

Guidance literature:: With trichlorophosphate; at 110 ℃; for 6h;
DOI:10.1021/jm00054a009

Reference yield:

: 27992-31-0
5,6-dimethyl-2(1H)-pyridone

: 65213-96-9
2,3-dimethyl-6-chloro-5-nitropyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / HNO₃; H₂SO₄ / 1 h / 5 °C

2: 53 percent / POCl₃; benzyltriethylammonium chloride / acetonitrile / 8 h / 80 °C

With sulfuric acid; N-benzyl-N,N,N-triethylammonium chloride; nitric acid; trichlorophosphate; In acetonitrile;
DOI:10.1021/jm0408621

Reference yield:

: 72716-80-4
1,2-dihydro-5,6-dimethyl-2-oxo-3-pyridinecarbonitrile

: 65213-96-9
2,3-dimethyl-6-chloro-5-nitropyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 47 percent / aq. HCl / 144 h / Heating

2: 100 percent / HNO₃; H₂SO₄ / 1 h / 5 °C

3: 53 percent / POCl₃; benzyltriethylammonium chloride / acetonitrile / 8 h / 80 °C

With hydrogenchloride; sulfuric acid; N-benzyl-N,N,N-triethylammonium chloride; nitric acid; trichlorophosphate; In acetonitrile;
DOI:10.1021/jm0408621