Z-Ser-Leu-Gly-NHMe

Base Information

Chemical Name:Z-Ser-Leu-Gly-NHMe
CAS No.:107540-70-5
Molecular Formula:C₃₂H₃₉N₄O₉P
Molecular Weight:654.657
Hs Code.:

Synonyms:Z-Ser-Leu-Gly-NHMe

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Z-Ser-Leu-Gly-NHMe

Chemical Property:

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Technology Process of Z-Ser-Leu-Gly-NHMe

There total 1 articles about Z-Ser-Leu-Gly-NHMe which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 107540-67-0
Z-Ser-Leu-Gly-NHMe

: 2524-64-3
chlorophosphoric acid diphenyl ester

: 107540-70-5
Z-Ser-Leu-Gly-NHMe

Guidance literature:: With pyridine; 1.) -10 deg C, 2.5 h, 2.) 4 deg C, 18 h;
DOI:10.1021/jo00385a023

Reference yield: 98.0%

: 107540-70-5
Z-Ser-Leu-Gly-NHMe

: 107540-71-6
H-Ser-Leu-Gly-NHMe*HCl

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol; ethanol; for 18h; under 1551.4 Torr;
DOI:10.1021/jo00385a023

Reference yield:

: 107540-70-5
Z-Ser-Leu-Gly-NHMe

: 107540-72-7
Ac-Leu-2-Ala-Ser-Leu-Gly-NHMe

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / H₂, 2N HCl / Pd/C / methanol; ethanol / 18 h / 1551.4 Torr

2: 34 percent / 1-hydroxybenzotriazole (HOBt), N-methylmorpholine, dicyclohexylcarbodiimide (DCC) / dimethylformamide / 1.) -10 deg C, 2 h, 2.) room temp., 18 h

With 4-methyl-morpholine; hydrogenchloride; hydrogen; benzotriazol-1-ol; dicyclohexyl-carbodiimide; palladium on activated charcoal; In methanol; ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jo00385a023