6-{benzyl-[(R)-2-(8-benzyloxy-2-oxo-1,2-dihydroquinolin-5-yl)-2-hydroxyethyl]amino}hexanoic acid {2-[(S)-3-(carbamoyldiphenylmethyl)pyrrolidin-1-yl]ethyl}methylamide

Base Information

• Chemical Name: 6-{benzyl-[(R)-2-(8-benzyloxy-2-oxo-1,2-dihydroquinolin-5-yl)-2-hydroxyethyl]amino}hexanoic acid {2-[(S)-3-(carbamoyldiphenylmethyl)pyrrolidin-1-yl]ethyl}methylamide
• CAS No.: 1361952-37-5
• Molecular Formula: C₅₂H₅₉N₅O₅
• Molecular Weight: 834.071

Synonyms:6-{benzyl-[(R)-2-(8-benzyloxy-2-oxo-1,2-dihydroquinolin-5-yl)-2-hydroxyethyl]amino}hexanoic acid {2-[(S)-3-(carbamoyldiphenylmethyl)pyrrolidin-1-yl]ethyl}methylamide

Chemical Property of 6-{benzyl-[(R)-2-(8-benzyloxy-2-oxo-1,2-dihydroquinolin-5-yl)-2-hydroxyethyl]amino}hexanoic acid {2-[(S)-3-(carbamoyldiphenylmethyl)pyrrolidin-1-yl]ethyl}methylamide

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Technology Process of 6-{benzyl-[(R)-2-(8-benzyloxy-2-oxo-1,2-dihydroquinolin-5-yl)-2-hydroxyethyl]amino}hexanoic acid {2-[(S)-3-(carbamoyldiphenylmethyl)pyrrolidin-1-yl]ethyl}methylamide

There total 1 articles about 6-{benzyl-[(R)-2-(8-benzyloxy-2-oxo-1,2-dihydroquinolin-5-yl)-2-hydroxyethyl]amino}hexanoic acid {2-[(S)-3-(carbamoyldiphenylmethyl)pyrrolidin-1-yl]ethyl}methylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-{benzyl-[(R)-2-(8-benzyloxy-2-oxo-1,2-dihydroquinolin-5-yl)-2-(tert-butyldimethylsilanyloxy)ethyl]amino}hexanoic acid {2-[(S)-3-(carbamoyldiphenylmethyl)pyrrolidin-1-yl]ethyl}methylamide (1361952-36-4) → 6-{benzyl-[(R)-2-(8-benzyloxy-2-oxo-1,2-dihydroquinolin-5-yl)-2-hydroxyethyl]amino}hexanoic acid {2-[(S)-3-(carbamoyldiphenylmethyl)pyrrolidin-1-yl]ethyl}methylamide (1361952-37-5)

Guidance literature:

With triethylamine tris(hydrogen fluoride); In dichloromethane; for 10h;

Reference yield:

6-{benzyl-[(R)-2-(8-benzyloxy-2-oxo-1,2-dihydroquinolin-5-yl)-2-hydroxyethyl]amino}hexanoic acid {2-[(S)-3-(carbamoyldiphenylmethyl)pyrrolidin-1-yl]ethyl}methylamide (1361952-37-5) → 6-[(R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]hexanoic acid {2-[(S)-3-(carbamoyldiphenylmethyl)pyrrolidin-1-yl]ethyl}methylamide

Guidance literature:

With hydrogen; palladium on activated carbon; In ethanol;

upstream raw materials:

6-{benzyl-[(R)-2-(8-benzyloxy-2-oxo-1,2-dihydroquinolin-5-yl)-2-(tert-butyldimethylsilanyloxy)ethyl]amino}hexanoic acid {2-[(S)-3-(carbamoyldiphenylmethyl)pyrrolidin-1-yl]ethyl}methylamide

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