4-Hydroxy-13-cis-Retinoic acid

Base Information

Chemical Name:4-Hydroxy-13-cis-Retinoic acid
CAS No.:75281-25-3
Molecular Formula:C₂₀H₂₈O₃
Molecular Weight:316.441
Hs Code.:

Synonyms:4-Hydroxy-13-cis-Retinoic acid

Suppliers and Price of 4-Hydroxy-13-cis-Retinoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Hydroxy-13-cis-retinoicAcid
2.5mg
$ 205.00

Medical Isotopes, Inc.
4-Hydroxy-13-cisretinoicAcid
10 mg
$ 1890.00

Medical Isotopes, Inc.
4-Hydroxy-13-cisretinoicAcid
1 mg
$ 390.00

Total 11 raw suppliers

Chemical Property of 4-Hydroxy-13-cis-Retinoic acid

Chemical Property:

Melting Point:>125°C (dec.)

Purity/Quality:

99%, ^*data from raw suppliers

4-Hydroxy-13-cis-retinoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 4-Hydroxy-13-cis-retinoic Acid is a metabolite of 13-cis-Retinoic Acid (R250000); a compound that is used for the treatment of severe acne and is presently being studied in conjunction with the treatment of photoaged skin.

Technology Process of 4-Hydroxy-13-cis-Retinoic acid

There total 15 articles about 4-Hydroxy-13-cis-Retinoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 38030-57-8,71748-58-8,100897-08-3,112924-95-5,150737-18-1,150737-19-2
13-cis-4-Oxoretinoic acid

: 75281-25-3
4-Hydroxy-13-cis-Retinoic acid

Guidance literature:: With sodium hydride; In ethanol; 1) 0 deg C, 15 min; 2) 20 deg C, 4 h;

Reference yield:

: 302-79-4
all-trans-retinoic-acid

: 38030-57-8,71748-58-8,100897-08-3,112924-95-5,150737-18-1,150737-19-2
4-ketoretinoic acid

: 66592-72-1,73366-04-8,75281-25-3,81176-70-7,150737-17-0
4-hydroxyretinoic acid

Guidance literature:: With rat reductase; NADPH; In aq. phosphate buffer; at 37 ℃; Kinetics; Enzymatic reaction;
DOI:10.1124/mol.117.111039

Reference yield:

: 302-79-4
all-trans-retinoic-acid

: 66592-72-1,73366-04-8,75281-25-3,81176-70-7,150737-17-0
4-hydroxyretinoic acid

Guidance literature:: With cytochrome P₄₅₀ 3A₄ enzyme; water; NADPH; In aq. phosphate buffer; at 37 ℃; pH=7.4; Reagent/catalyst; Kinetics; Enzymatic reaction;
DOI:10.1074/jbc.M112.404475