Oxiranecarboxaldehyde, 3-phenyl-, (2R,3S)-rel- (9CI)

Base Information

• Chemical Name: Oxiranecarboxaldehyde, 3-phenyl-, (2R,3S)-rel- (9CI)
• CAS No.: 71403-94-6
• Molecular Formula: C9H8 O2
• Molecular Weight: 148.161
• Mol file: 71403-94-6.mol

Synonyms:Oxiranecarboxaldehyde,3-phenyl-, (2R,3S)-rel- (9CI); Oxiranecarboxaldehyde, 3-phenyl-, trans-;trans-2-Phenyloxiranecarboxaldehyde; trans-3-Phenyloxirane-2-carboxaldehyde;trans-Cinnamaldehyde epoxide

Chemical Property of Oxiranecarboxaldehyde, 3-phenyl-, (2R,3S)-rel- (9CI)

Chemical Property:

• PSA: 29.60000
• LogP: 1.32540

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Oxiranecarboxaldehyde, 3-phenyl-, (2R,3S)-rel- (9CI)

There total 57 articles about Oxiranecarboxaldehyde, 3-phenyl-, (2R,3S)-rel- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

3-phenyl-propenal (104-55-2) → 2,3-epoxy-3-phenylpropanal (71403-94-6)

Guidance literature:

With sodium hydroxide; In 1,4-dioxane; water; for 8h; Reflux;

DOI:10.1016/j.mencom.2010.03.017

Reference yield: 90.0%

(E)-3-phenylpropenal (14371-10-9) → 2,3-epoxy-3-phenylpropanal (71403-94-6)

Guidance literature:

With sodium hydroxide; dihydrogen peroxide; In methanol; at 25 ℃; for 0.333333h;

DOI:10.1016/j.tet.2007.03.167

Reference yield: 80.0%

(2E)-3-phenyl-2-propen-1-ol (4407-36-7) → (2S,3S)-3-phenyloxirane-2-carbaldehyde (5693-99-2,71403-94-6,99773-54-3,119951-98-3,121651-02-3,126720-47-6)

Guidance literature:

DOI:10.1016/S0040-4039(00)80680-2

upstream raw materials:

(E)-3-phenylpropenal

3-hydroxy-5-phenyl-1,2-dioxolane

cinnamylamine 2,3-oxide hydrochloride

3-phenyl-propenal

Downstream raw materials:

2-phenyl-3-vinyloxirane

styrene oxide

benzaldehyde

rac-6-phenyl-5,6-dihydro-2H-pyran-2-one

Refernces

• 1、 Artok, Levent,Bilgi, Yasemin,Ku?, Melih. "Palladium-catalysed regio- And stereoselective arylative substitution of γ,δ-epoxy-α,β-unsaturated esters and amides by sodium tetraaryl borates". supporting information. p. 6378 - 6383. Retrieved 2020/09/07.
• 2、 Dai, Su-Yi,Lai, Fang,Li, Wei-Guang,Li, Yuan-Lin,Liang, Min,Liu, Xiong-Min,Ma, Li,Yu, Chang. "Characteristics and hazards of the cinnamaldehyde oxidation process". . p. 19124 - 19133. Retrieved 2020/06/08.