(2-Benzo[1,3]dioxol-5-yl-cyclopropyl)-(3,4-dimethoxy-phenyl)-methanone

Base Information

• Chemical Name: (2-Benzo[1,3]dioxol-5-yl-cyclopropyl)-(3,4-dimethoxy-phenyl)-methanone
• CAS No.: 76934-56-0
• Molecular Formula: C₁₉H₁₈O₅
• Molecular Weight: 326.349
• Mol file: 76934-56-0.mol

Synonyms:(2-Benzo[1,3]dioxol-5-yl-cyclopropyl)-(3,4-dimethoxy-phenyl)-methanone

Chemical Property of (2-Benzo[1,3]dioxol-5-yl-cyclopropyl)-(3,4-dimethoxy-phenyl)-methanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2-Benzo[1,3]dioxol-5-yl-cyclopropyl)-(3,4-dimethoxy-phenyl)-methanone

There total 1 articles about (2-Benzo[1,3]dioxol-5-yl-cyclopropyl)-(3,4-dimethoxy-phenyl)-methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-1-(3,4-dimethoxyphenyl)-3-(3,4-methylenedioxyphenyl)-prop-2-en-1-one (51116-22-4) + trimethylsulfoxonium iodide (1774-47-6) → (2-Benzo[1,3]dioxol-5-yl-cyclopropyl)-(3,4-dimethoxy-phenyl)-methanone (76934-56-0)

Guidance literature:

With sodium hydride; dimethyl sulfoxide; Yield given. Multistep reaction; 1) 20 deg C, 15 - 20 min; 2) dimethyl sulphoxide, room temperature, 0.5 - 1 h;

DOI:10.1039/P19810002920

Reference yield: 36.0%

(2-Benzo[1,3]dioxol-5-yl-cyclopropyl)-(3,4-dimethoxy-phenyl)-methanone (76934-56-0) → 6,7-dimethoxy-4-(3,4-methylenedioxyphenyl)-3,4-dihydronaphthalen-1(2H)-one (80816-89-3) + 3,4-dimethoxyphenyl 3-hydroxy-3-(3,4-methylenedioxyphenyl)propyl ketone (76934-69-5)

Guidance literature:

With tin(IV) chloride; In nitromethane; for 30h; Ambient temperature;

DOI:10.1039/P19810002920

Reference yield: 35.0%

((1S,2S)-2-Benzo[1,3]dioxol-5-yl-cyclopropyl)-(3,4-dimethoxy-phenyl)-methanone (76934-56-0) → 6,7-dimethoxy-4-(3,4-methylenedioxyphenyl)-3,4-dihydronaphthalen-1(2H)-one (80816-89-3) + 3,4-dimethoxyphenyl 3-hydroxy-3-(3,4-methylenedioxyphenyl)propyl ketone (76934-69-5)

Guidance literature:

With tin(IV) chloride; In benzene; for 47h; Ambient temperature;

upstream raw materials:

(E)-1-(3,4-dimethoxyphenyl)-3-(3,4-methylenedioxyphenyl)-prop-2-en-1-one

trimethylsulfoxonium iodide

Downstream raw materials:

6,7-dimethoxy-4-(3,4-methylenedioxyphenyl)-3,4-dihydronaphthalen-1(2H)-one

3,4-dimethoxyphenyl 3-hydroxy-3-(3,4-methylenedioxyphenyl)propyl ketone