ISOSORBIDEDI-N-HEXANOATE

Base Information

• Chemical Name: ISOSORBIDEDI-N-HEXANOATE
• CAS No.: 64896-69-1
• Molecular Formula: C₁₈H₃₀O₆
• Molecular Weight: 342.433
• Mol file: 64896-69-1.mol

Synonyms:Hexanoicacid, diester with 1,4:3,6-dianhydrosorbitol (5CI); Furo[3,2-b]furan,D-glucitol deriv.; Isosorbide dihexanoate

Chemical Property of ISOSORBIDEDI-N-HEXANOATE

Chemical Property:

• Boiling Point: 198 - 201 °C (1 mmHg)
• PSA: 71.06000
• LogP: 2.76820

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ISOSORBIDEDI-N-HEXANOATE

There total 6 articles about ISOSORBIDEDI-N-HEXANOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

hexanoic acid (142-62-1) + Isosorbide (652-67-5) → isosorbide dihexanoate (64896-69-1)

Guidance literature:

With lead(II) oxide; at 180 ℃; for 15h;

Reference yield: 57.0%

n-hexanoic anhydride (2051-49-2) + Isosorbide (652-67-5) → isosorbide dihexanoate (64896-69-1) + isosorbide 2-O-hexanoate (84207-85-2,112244-98-1) + isosorbide 5-O-hexanoate (84207-85-2,112244-98-1)

Guidance literature:

at 120 - 140 ℃; for 1h;

DOI:10.1055/s-1987-27878

Reference yield: 13.0%

→ isosorbide dihexanoate (64896-69-1) + isosorbide 2-O-hexanoate (84207-85-2,112244-98-1) + isosorbide 5-O-hexanoate (84207-85-2,112244-98-1)

Guidance literature:

With phosphotungstic acid; In toluene; at 170 ℃; for 6h; Temperature; Solvent; Reagent/catalyst; Overall yield = 84 mol; Inert atmosphere; Sealed tube;

upstream raw materials:

hexanoic acid

Isosorbide

n-hexanoic anhydride

D-sorbitol

Refernces

• 1、 -. "Preparation method of dicarboxylic isosorbide". Paragraph 0032. . Retrieved 2017/07/05.
• 2、 -. "METHOD FOR MEASURING REACTION RATIO OF ISOSORBIDE ALKANOATE". Paragraph 0081; 0082. . Retrieved 2017/06/02.