N-<2-<(2-amino-2-oxoethyl)amino>-3-pyridyl>-4-chlorobenzamide

Base Information

• Chemical Name: N-<2-<(2-amino-2-oxoethyl)amino>-3-pyridyl>-4-chlorobenzamide
• CAS No.: 118699-09-5
• Molecular Formula: C₁₄H₁₃ClN₄O₂
• Molecular Weight: 304.736
• Mol file: 118699-09-5.mol

Synonyms:N-<2-<(2-amino-2-oxoethyl)amino>-3-pyridyl>-4-chlorobenzamide

Chemical Property of N-<2-<(2-amino-2-oxoethyl)amino>-3-pyridyl>-4-chlorobenzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-<2-<(2-amino-2-oxoethyl)amino>-3-pyridyl>-4-chlorobenzamide

There total 3 articles about N-<2-<(2-amino-2-oxoethyl)amino>-3-pyridyl>-4-chlorobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Chloro-3-nitropyridine (5470-18-8,34515-82-7) → N-<2-<(2-amino-2-oxoethyl)amino>-3-pyridyl>-4-chlorobenzamide (118699-09-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 73 percent / Et₃N / acetonitrile / 16.5 h / Heating

2: H₂ / 5percent Pd/C / tetrahydrofuran / 1 h / Ambient temperature

3: Et₃N / acetone / Ambient temperature

With hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; acetone; acetonitrile;

DOI:10.1021/jm00114a007

Reference yield:

2-<(3-nitro-2-pyridinyl)amino>acetamide (118699-03-9) → N-<2-<(2-amino-2-oxoethyl)amino>-3-pyridyl>-4-chlorobenzamide (118699-09-5)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / 5percent Pd/C / tetrahydrofuran / 1 h / Ambient temperature

2: Et₃N / acetone / Ambient temperature

With hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; acetone;

DOI:10.1021/jm00114a007

Reference yield:

4-chloro-benzoyl chloride (122-01-0) + 3-amino-2-<(2-amino-2-oxoethyl)amino>pyridine (118699-05-1) → N-<2-<(2-amino-2-oxoethyl)amino>-3-pyridyl>-4-chlorobenzamide (118699-09-5)

Guidance literature:

With triethylamine; In acetone; Yield given; Ambient temperature;

DOI:10.1021/jm00114a007

upstream raw materials:

4-chloro-benzoyl chloride

3-amino-2-<(2-amino-2-oxoethyl)amino>pyridine

2-Chloro-3-nitropyridine

2-<(3-nitro-2-pyridinyl)amino>acetamide

Downstream raw materials:

2-(4-chlorophenyl)-3H-imidazo[4,5-b]pyridine-3-acetamide-4-oxide

2-(4-chlorophenyl)-3H-imidazo<4,5-b>pyridine-3-acetamide