Technology Process of Benzyl-4-O-(3,4-di-O-acetyl-2,6-didesoxy-β-D-arabino-hexopyranosyl)-2,6-didesoxy-3-O-benzyl-α-D-arabino-hexopyranosid
There total 14 articles about Benzyl-4-O-(3,4-di-O-acetyl-2,6-didesoxy-β-D-arabino-hexopyranosyl)-2,6-didesoxy-3-O-benzyl-α-D-arabino-hexopyranosid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
azobisisobutyronitrile; tri-n-butyl-tin hydride;
In
toluene;
at 70 ℃;
for 3h;
DOI:10.1021/jo00191a006
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 90.5 percent / pyridine / Ambient temperature
2: BF3-OEt2 / CH2Cl2 / 2 h / Ambient temperature
3: CH3ONa / methanol
4: 28 percent / tetrabutyl-ammonium bromide, aq.KOH / 120 h
5: 56.5 percent / Ag-triflate, collidine / toluene; CH2Cl2; nitromethane / 1) 6h, -20 to -10 deg 2) roomtemp.
6: 74 percent / α,α'-azobis(isobutyronitrile), tributylstannane / toluene / 3 h / 70 °C
With
pyridine; 2,3,5-trimethyl-pyridine; potassium hydroxide; azobisisobutyronitrile; boron trifluoride diethyl etherate; tetrabutylammomium bromide; tri-n-butyl-tin hydride; silver trifluoromethanesulfonate;
sodium methylate;
In
methanol; nitromethane; dichloromethane; toluene;
DOI:10.1021/jo00191a006
- Guidance literature:
-
Multi-step reaction with 4 steps
1: CH3ONa / methanol
2: 28 percent / tetrabutyl-ammonium bromide, aq.KOH / 120 h
3: 56.5 percent / Ag-triflate, collidine / toluene; CH2Cl2; nitromethane / 1) 6h, -20 to -10 deg 2) roomtemp.
4: 74 percent / α,α'-azobis(isobutyronitrile), tributylstannane / toluene / 3 h / 70 °C
With
2,3,5-trimethyl-pyridine; potassium hydroxide; azobisisobutyronitrile; tetrabutylammomium bromide; tri-n-butyl-tin hydride; silver trifluoromethanesulfonate;
sodium methylate;
In
methanol; nitromethane; dichloromethane; toluene;
DOI:10.1021/jo00191a006
