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78185-01-0

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78185-01-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 78185-01-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,1,8 and 5 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 78185-01:
(7*7)+(6*8)+(5*1)+(4*8)+(3*5)+(2*0)+(1*1)=150
150 % 10 = 0
So 78185-01-0 is a valid CAS Registry Number.

78185-01-0Relevant articles and documents

Three new isoflavonoid glycosides from the mangrove-derived actinomycete micromonospora aurantiaca 110B

Wang, Rui-Jun,Zhang, Shao-Yong,Ye, Yang-Hui,Yu, Zhen,Qi, Huan,Zhang, Hui,Xue, Zheng-Lian,Wang, Ji-Dong,Wu, Min

, (2019)

The mangrove ecosystem is a rich resource for the discovery of actinomycetes with potential applications in pharmaceutical science. Besides the genus Streptomyces, Micromonospora is also a source of new bioactive agents. We screened Micromonospora from the rhizosphere soil of mangrove plants in Fujian province, China, and 51 strains were obtained. Among them, the extracts of 12 isolates inhibited the growth of human lung carcinoma A549 cells. Strain 110B exhibited better cytotoxic activity, and its bioactive constituents were investigated. Consequently, three new isoflavonoid glycosides, daidzein-40-(2-deoxy-a-l-fucopyranoside) (1), daidzein-7-(2-deoxy-a-l-fucopyranoside) (2), and daidzein-40,7-di-(2-deoxy-a-l-fucopyranoside) (3) were isolated from the fermentation broth of strain 110B. The structures of the new compounds were determined by spectroscopic methods, including 1D and 2D nuclear magnetic resonance (NMR) and high-resolution electrospray ionization mass spectrometry (HR-ESIMS). The result of medium-changing experiments implicated that these new compounds were microbial biotransformation products of strain M. aurantiaca 110B. The three compounds displayed moderate cytotoxic activity to the human lung carcinoma cell line A549, hepatocellular liver carcinoma cell line HepG2, and the human colon tumor cell line HCT116, whereas none of them showed antifungal or antibacterial activities.

Neuroprotective polyhydroxypregnane glycosides from Cynanchum otophyllum

Zhao, Zhi-Min,Sun, Zhang-Hua,Chen, Mei-Hui,Liao, Qiong,Tan, Ming,Zhang, Xin-Wen,Zhu, Han-Dong,Pi, Rong-Biao,Yin, Sheng

, p. 1015 - 1020 (2013/10/21)

Five new polyhydroxypregnane glycosides, namely cynanotosides A-E (1-5), together with two known analogues, deacetylmetaplexigenin (6) and cynotophylloside H (7), were isolated from the roots of Cynanchum otophyllum. Their structures were established by spectroscopic methods and acid hydrolysis. The neuroprotective effects of compounds 1-7 against glutamate-, hydrogen peroxide-, and homocysteic acid (HCA)-induced cell death were tested by MTT assay in a hippocampal neuronal cell line HT22. Compounds 1, 2, and 7 exhibited protective activity against HCA-induced cell death in a dose-dependent manner ranging from 1 to 30 μM, which may explain the Traditional Chinese Medicine (TCM) use of this plant for the treatment of epilepsy.

Steroidal glycosides from the aerial part of Asclepias incarnata

Warashina, Tsutomu,Noro, Tadataka

, p. 485 - 498 (2007/10/03)

The aerial part of Asclepias incarnata afforded 34 pregnane glycosides. These were confirmed to have lineolon, isolineolon, ikemagenin, 12-O- nicotinoyllineolon, deacylmetaplexigenin, metaplexigenin, rostratamine, 12-O- acetyllineolon, 15β-hydroxylineolon

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