cyclopentyl N-(3-{[{[2,4-dihydroxy-5-(propan-2-yl)-phenyl]carbonyl}(methyl)amino]methyl}benzyl)-L-leucinate

Base Information

Chemical Name:cyclopentyl N-(3-{[{[2,4-dihydroxy-5-(propan-2-yl)-phenyl]carbonyl}(methyl)amino]methyl}benzyl)-L-leucinate
CAS No.:1351814-64-6
Molecular Formula:C₃₀H₄₂N₂O₅
Molecular Weight:510.674
Hs Code.:

Synonyms:cyclopentyl N-(3-{[{[2,4-dihydroxy-5-(propan-2-yl)-phenyl]carbonyl}(methyl)amino]methyl}benzyl)-L-leucinate

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Chemical Property of cyclopentyl N-(3-{[{[2,4-dihydroxy-5-(propan-2-yl)-phenyl]carbonyl}(methyl)amino]methyl}benzyl)-L-leucinate

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Technology Process of cyclopentyl N-(3-{[{[2,4-dihydroxy-5-(propan-2-yl)-phenyl]carbonyl}(methyl)amino]methyl}benzyl)-L-leucinate

There total 10 articles about cyclopentyl N-(3-{[{[2,4-dihydroxy-5-(propan-2-yl)-phenyl]carbonyl}(methyl)amino]methyl}benzyl)-L-leucinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 3.0%

: 1351815-62-7
cyclopentyl N-(3-{[{[2,4-bis(benzyloxy)-5-(prop-1-en-2-yl)phenyl]carbonyl}(methyl)amino]methyl}benzyl)-L-leucinate

: 1351814-64-6
cyclopentyl N-(3-{[{[2,4-dihydroxy-5-(propan-2-yl)-phenyl]carbonyl}(methyl)amino]methyl}benzyl)-L-leucinate

Guidance literature:: With hydrogen; potassium carbonate; palladium 10% on activated carbon; at 20 ℃;

Reference yield:

: 912545-08-5
2,4-bis-benzyloxy-5-isopropenyl-benzoic acid methyl ester

: 1351814-64-6
cyclopentyl N-(3-{[{[2,4-dihydroxy-5-(propan-2-yl)-phenyl]carbonyl}(methyl)amino]methyl}benzyl)-L-leucinate

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium hydroxide; methanol / 20 h / 75 °C

1.2: 0.5 h / 20 °C

2.1: triethylamine; HATU / dichloromethane / 1 h / 20 °C

3.1: potassium carbonate; hydrogen / palladium 10% on activated carbon / 20 °C

With methanol; hydrogen; potassium carbonate; triethylamine; HATU; potassium hydroxide; palladium 10% on activated carbon; In dichloromethane;

Reference yield:

: 82072-23-9
3-(bromomethyl)benzaldehyde

: 1351814-64-6
cyclopentyl N-(3-{[{[2,4-dihydroxy-5-(propan-2-yl)-phenyl]carbonyl}(methyl)amino]methyl}benzyl)-L-leucinate

Guidance literature:: Multi-step reaction with 4 steps

1: sodium tris(acetoxy)borohydride / 1,1-dichloroethane / 0.5 h / 20 °C

2: sodium hydrogencarbonate / ethanol / 18 h / 20 °C

3: triethylamine; HATU / dichloromethane / 1 h / 20 °C

4: potassium carbonate; hydrogen / palladium 10% on activated carbon / 20 °C

With hydrogen; sodium tris(acetoxy)borohydride; sodium hydrogencarbonate; potassium carbonate; triethylamine; HATU; palladium 10% on activated carbon; In 1,1-dichloroethane; ethanol; dichloromethane;