Pyrrolidine, 3-(phenylmethoxy)-2-(phenylmethoxy)methyl-1-(phenylmethyl)-, (2R,3S)-

Base Information

Chemical Name:Pyrrolidine, 3-(phenylmethoxy)-2-(phenylmethoxy)methyl-1-(phenylmethyl)-, (2R,3S)-
CAS No.:294188-27-5
Molecular Formula:C₂₆H₂₉NO₂
Molecular Weight:387.522
Hs Code.:
Mol file:294188-27-5.mol

Synonyms:N-benzyl-3,5-di-O-benzyl-1,2,4-trideoxy-1,4-imino-D-erythro-pentitol

Suppliers and Price of Pyrrolidine, 3-(phenylmethoxy)-2-(phenylmethoxy)methyl-1-(phenylmethyl)-, (2R,3S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Pyrrolidine, 3-(phenylmethoxy)-2-(phenylmethoxy)methyl-1-(phenylmethyl)-, (2R,3S)-

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of Pyrrolidine, 3-(phenylmethoxy)-2-(phenylmethoxy)methyl-1-(phenylmethyl)-, (2R,3S)-

There total 9 articles about Pyrrolidine, 3-(phenylmethoxy)-2-(phenylmethoxy)methyl-1-(phenylmethyl)-, (2R,3S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 100-46-9
benzylamine

: 1054683-61-2
methanesulfonic acid (1S,2S)-2-benzyloxy-1-benzyloxymethyl-4-methanesulfonyloxybutyl ester

: 294188-27-5
N-benzyl-3,5-di-O-benzyl-1,2,4-trideoxy-1,4-imino-D-erythro-pentitol

Guidance literature:: In N,N-dimethyl-formamide; at 50 - 60 ℃; for 16h;
DOI:10.1080/07328300008544100

Reference yield:

: 81927-55-1
O-benzyl 2,2,2-trichloroacetimidate

: 294188-27-5
N-benzyl-3,5-di-O-benzyl-1,2,4-trideoxy-1,4-imino-D-erythro-pentitol

Guidance literature:: Multi-step reaction with 4 steps

1: 69 percent / CF₃SO₃H / dioxane / 20 °C / pH 2.5 - 3

2: 98 percent / LiAlH₄ / tetrahydrofuran / 1.25 h / 0 - 20 °C

3: 100 percent / pyridine / 1.5 h / 0 - 20 °C

4: 87 percent / dimethylformamide / 16 h / 50 - 60 °C

With pyridine; lithium aluminium tetrahydride; trifluorormethanesulfonic acid; In tetrahydrofuran; 1,4-dioxane; N,N-dimethyl-formamide; 1: Esterification / 2: Ring cleavage / 3: Condensation / 4: cyclocondensation;
DOI:10.1080/07328300008544100

Reference yield:

: 82130-86-7
2,5-di-O-tosyl-D-ribono-1,4-lactone

: 294188-27-5
N-benzyl-3,5-di-O-benzyl-1,2,4-trideoxy-1,4-imino-D-erythro-pentitol

Guidance literature:: Multi-step reaction with 6 steps

1: 95 percent / Br₂; hydrazine / H₂O; dioxane / 0 - 20 °C

2: aq. KOH / 20 °C

3: 69 percent / CF₃SO₃H / dioxane / 20 °C / pH 2.5 - 3

4: 98 percent / LiAlH₄ / tetrahydrofuran / 1.25 h / 0 - 20 °C

5: 100 percent / pyridine / 1.5 h / 0 - 20 °C

6: 87 percent / dimethylformamide / 16 h / 50 - 60 °C

With pyridine; potassium hydroxide; lithium aluminium tetrahydride; trifluorormethanesulfonic acid; bromine; hydrazine; In tetrahydrofuran; 1,4-dioxane; water; N,N-dimethyl-formamide; 1: Reduction / 2: Hydrolysis / 3: Esterification / 4: Ring cleavage / 5: Condensation / 6: cyclocondensation;
DOI:10.1080/07328300008544100