2-Formyl-3-methoxy-benzoic acid 3-benzyloxycarbonyl-phenyl ester

Base Information

• Chemical Name: 2-Formyl-3-methoxy-benzoic acid 3-benzyloxycarbonyl-phenyl ester
• CAS No.: 437614-10-3
• Molecular Formula: C₂₃H₁₈O₆
• Molecular Weight: 390.392
• Mol file: 437614-10-3.mol

Synonyms:2-Formyl-3-methoxy-benzoic acid 3-benzyloxycarbonyl-phenyl ester

Chemical Property of 2-Formyl-3-methoxy-benzoic acid 3-benzyloxycarbonyl-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Formyl-3-methoxy-benzoic acid 3-benzyloxycarbonyl-phenyl ester

There total 6 articles about 2-Formyl-3-methoxy-benzoic acid 3-benzyloxycarbonyl-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3-Methoxy-2-vinyl-benzoic acid 3-benzyloxycarbonyl-phenyl ester (437614-09-0) → 2-Formyl-3-methoxy-benzoic acid 3-benzyloxycarbonyl-phenyl ester (437614-10-3)

Guidance literature:

3-Methoxy-2-vinyl-benzoic acid 3-benzyloxycarbonyl-phenyl ester; With ozone; In dichloromethane; at -78 ℃;

With triphenylphosphine; In dichloromethane; at -78 - 20 ℃;

DOI:10.1016/S0040-4020(02)00096-0

Reference yield:

3-methoxy-2-vinylbenzoic acid (64957-80-8) → 2-Formyl-3-methoxy-benzoic acid 3-benzyloxycarbonyl-phenyl ester (437614-10-3)

Guidance literature:

Multi-step reaction with 3 steps

1.1: oxalyl chloride / CH₂Cl₂; dimethylformamide / 1.5 h

2.1: 198 mg / Et₃N / CH₂Cl₂ / 2 h

3.1: O₃ / CH₂Cl₂ / -78 °C

3.2: 100 percent / Ph₃P / CH₂Cl₂ / -78 - 20 °C

With oxalyl dichloride; ozone; triethylamine; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/S0040-4020(02)00096-0

Reference yield:

3-Benzyloxycarbonyl-phenol (77513-40-7) → 2-Formyl-3-methoxy-benzoic acid 3-benzyloxycarbonyl-phenyl ester (437614-10-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 198 mg / Et₃N / CH₂Cl₂ / 2 h

2.1: O₃ / CH₂Cl₂ / -78 °C

2.2: 100 percent / Ph₃P / CH₂Cl₂ / -78 - 20 °C

With ozone; triethylamine; In dichloromethane;

DOI:10.1016/S0040-4020(02)00096-0

upstream raw materials:

3-Methoxy-2-vinyl-benzoic acid 3-benzyloxycarbonyl-phenyl ester

3-methoxy-2-vinylbenzoic acid

3-Benzyloxycarbonyl-phenol

benzyl bromide

Downstream raw materials:

4-methoxyphthalide

3-Benzyloxycarbonyl-phenol