5-(3-trifluoromethyl-phenyl)-furan-2-carboxylic acid 3-fluoro-4-methanesulfonylamino-5-methyl-benzylamide

Base Information

• Chemical Name: 5-(3-trifluoromethyl-phenyl)-furan-2-carboxylic acid 3-fluoro-4-methanesulfonylamino-5-methyl-benzylamide
• CAS No.: 1202642-78-1
• Molecular Formula: C₂₁H₁₈F₄N₂O₄S
• Molecular Weight: 470.445
• Mol file: 1202642-78-1.mol

Synonyms:5-(3-trifluoromethyl-phenyl)-furan-2-carboxylic acid 3-fluoro-4-methanesulfonylamino-5-methyl-benzylamide

Chemical Property of 5-(3-trifluoromethyl-phenyl)-furan-2-carboxylic acid 3-fluoro-4-methanesulfonylamino-5-methyl-benzylamide

Chemical Property:

Purity/Quality:

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Technology Process of 5-(3-trifluoromethyl-phenyl)-furan-2-carboxylic acid 3-fluoro-4-methanesulfonylamino-5-methyl-benzylamide

There total 1 articles about 5-(3-trifluoromethyl-phenyl)-furan-2-carboxylic acid 3-fluoro-4-methanesulfonylamino-5-methyl-benzylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

5-(3-trifluoromethylphenyl)furan-2-carboxylic acid (54022-99-0) + N-(4-aminomethyl-2-fluoro-6-methyl-phenyl)-methanesulfonamide hydrochloride (911143-75-4) → 5-(3-trifluoromethyl-phenyl)-furan-2-carboxylic acid 3-fluoro-4-methanesulfonylamino-5-methyl-benzylamide (1202642-78-1)

Guidance literature:

With 4-methyl-morpholine; 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; In tetrahydrofuran; at 20 ℃;

upstream raw materials:

5-(3-trifluoromethylphenyl)furan-2-carboxylic acid

N-(4-aminomethyl-2-fluoro-6-methyl-phenyl)-methanesulfonamide hydrochloride