(3S,4R)-4-Benzyloxycarbonylamino-5-methyl-3-triisopropylsilanyloxy-hexanoic acid (S)-1-allyloxycarbonyl-2-methyl-propyl ester

Base Information

Chemical Name:(3S,4R)-4-Benzyloxycarbonylamino-5-methyl-3-triisopropylsilanyloxy-hexanoic acid (S)-1-allyloxycarbonyl-2-methyl-propyl ester
CAS No.:325687-67-0
Molecular Formula:C₃₂H₅₃NO₇Si
Molecular Weight:591.861
Hs Code.:

Synonyms:(3S,4R)-4-Benzyloxycarbonylamino-5-methyl-3-triisopropylsilanyloxy-hexanoic acid (S)-1-allyloxycarbonyl-2-methyl-propyl ester

Suppliers and Price of (3S,4R)-4-Benzyloxycarbonylamino-5-methyl-3-triisopropylsilanyloxy-hexanoic acid (S)-1-allyloxycarbonyl-2-methyl-propyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3S,4R)-4-Benzyloxycarbonylamino-5-methyl-3-triisopropylsilanyloxy-hexanoic acid (S)-1-allyloxycarbonyl-2-methyl-propyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3S,4R)-4-Benzyloxycarbonylamino-5-methyl-3-triisopropylsilanyloxy-hexanoic acid (S)-1-allyloxycarbonyl-2-methyl-propyl ester

There total 11 articles about (3S,4R)-4-Benzyloxycarbonylamino-5-methyl-3-triisopropylsilanyloxy-hexanoic acid (S)-1-allyloxycarbonyl-2-methyl-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 178113-56-9
L-2-hydroxy-3-methylbutanoic acid allyl ester

: 325687-66-9
(3S,4R)-4-benzyloxycarbonylamino-3-(triisopropylsilanyloxy)heptanoic acid

: 325687-67-0
(3S,4R)-4-Benzyloxycarbonylamino-5-methyl-3-triisopropylsilanyloxy-hexanoic acid (S)-1-allyloxycarbonyl-2-methyl-propyl ester

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane;
DOI:10.1016/S0040-4039(00)01409-X

Reference yield:

: 17407-55-5
(S)-2-Hydroxy-3-methylbutanoic acid

: 325687-67-0
(3S,4R)-4-Benzyloxycarbonylamino-5-methyl-3-triisopropylsilanyloxy-hexanoic acid (S)-1-allyloxycarbonyl-2-methyl-propyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / K₂CO₃ / Bu₄NI / dimethylformamide / 1 h / 20 °C

2: 60 percent / EDAC*HCl; DMAP / CH₂Cl₂ / 0 - 20 °C

With dmap; potassium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; tetra-(n-butyl)ammonium iodide; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja010222c

Reference yield:

: 72-18-4,25609-85-2,7004-03-7,921-10-8
L-valine

: 325687-67-0
(3S,4R)-4-Benzyloxycarbonylamino-5-methyl-3-triisopropylsilanyloxy-hexanoic acid (S)-1-allyloxycarbonyl-2-methyl-propyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 78 percent / 1N aq. H₂SO₄; NaNO₂ / 0 - 20 °C

2: 96 percent / K₂CO₃ / Bu₄NI / dimethylformamide / 1 h / 20 °C

3: 60 percent / EDAC*HCl; DMAP / CH₂Cl₂ / 0 - 20 °C

With dmap; sulfuric acid; potassium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium nitrite; tetra-(n-butyl)ammonium iodide; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja010222c