2-Methyl-1,2,3,4-tetrahydronaphthalen-1-ol

Base Information

• Chemical Name: 2-Methyl-1,2,3,4-tetrahydronaphthalen-1-ol
• CAS No.: 32281-70-2
• Molecular Formula: C₁₁H₁₄O
• Molecular Weight: 162.232
• DSSTox Substance ID: DTXSID301268559
• Nikkaji Number: J108.930G
• Mol file: 32281-70-2.mol

Synonyms:2-methyl-1,2,3,4-tetrahydronaphthalen-1-ol;32281-70-2;1,2,3,4-Tetrahydro-2-methyl-1-naphthol;1,2,3,4-tetrahydro-2-methylnaphthalen-1-ol;1-Naphthol, 1,2,3,4-tetrahydro-2-methyl-;SCHEMBL2190921;AMY6134;DTXSID301268559;ZB1755;AKOS011021388;CS-0068753;1,2,3,4-Tetrahydro-2-methyl-1-naphthalenol;2-Methyl-1,2,3,4-tetrahydro-1-naphthalenol #

Chemical Property of 2-Methyl-1,2,3,4-tetrahydronaphthalen-1-ol

Chemical Property:

• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 162.104465066
• Heavy Atom Count: 12
• Complexity: 155

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1CCC2=CC=CC=C2C1O

Technology Process of 2-Methyl-1,2,3,4-tetrahydronaphthalen-1-ol

There total 2 articles about 2-Methyl-1,2,3,4-tetrahydronaphthalen-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methyl-1-tetralone-2-carboxylic acid benzyl ester (188359-88-8) → 2-methyl-1-tetralone (1590-08-5) + 1,2,3,4-tetrahydro-2-methylnaphthalen-1-ol (32281-70-2) + (+/-)-2-hydroxy-2-methyl-3,4-dihydro-2H-naphthalen-1-one (78506-98-6)

Guidance literature:

With palladium on activated charcoal; hydrogen; In acetonitrile; at 20 ℃; under 750.075 Torr;

DOI:10.1039/c3nj00457k

Reference yield:

2-methylnaphthalen-1-ol (7469-77-4) → 2-methyl-1-tetralone (1590-08-5) + 1,2,3,4-tetrahydro-2-methylnaphthalen-1-ol (32281-70-2) + 2-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol (41059-12-5)

Guidance literature:

With hydrogen; palladium on activated charcoal; In n-heptane; under 3750.3 Torr; Further Variations:; Solvents; Product distribution;

DOI:10.1246/cl.2006.780

Reference yield:

2-methyl-1,2,3,4-tetrahydronaphthalen-1-ol (3344-46-5,14833-74-0,32281-70-2,38157-10-7,38157-13-0,38157-18-5,65941-81-3) → (+/-)-3,5-dinitro-benzoic acid-(trans-2-methyl-1,2,3,4-tetrahydro-[1]naphthyl ester)

Guidance literature:

DOI:10.1021/ja01163a109

upstream raw materials:

2-methylnaphthalen-1-ol

2-methyl-1-tetralone-2-carboxylic acid benzyl ester

Refernces

• 1、 Mine, Eiichi,Hiyoshi, Norihito,Sato, Osamu,Rode, Chandrashekhar V.,Shirai, Masayuki. "Selective hydrogenation of naphthols to tetralones over supported palladium catalysts in supercritical carbon dioxide solvent". . p. 780 - 781. Retrieved 2007/10/03.