5-methoxy-4-methyl-2-nitrobenzoic acid

Base Information

• Chemical Name: 5-methoxy-4-methyl-2-nitrobenzoic acid
• CAS No.: 857599-32-7
• Molecular Formula: C₉H₉NO₅
• Molecular Weight: 211.174
• Mol file: 857599-32-7.mol

Synonyms:5-methoxy-4-methyl-2-nitrobenzoic acid

Chemical Property of 5-methoxy-4-methyl-2-nitrobenzoic acid

Chemical Property:

• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

5-Methoxy-4-Methyl-2-NitrobenzoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-methoxy-4-methyl-2-nitrobenzoic acid

There total 3 articles about 5-methoxy-4-methyl-2-nitrobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-hydroxy-4-methylbenzonitrile (3816-66-8) → 5-methoxy-4-methyl-2-nitrobenzoic acid (857599-32-7)

Guidance literature:

Multi-step reaction with 3 steps

1: aqueous HNO₃

2: aqueous NaOH

With sodium hydroxide; nitric acid;

DOI:10.1039/jr9530003646

Reference yield:

5-hydroxy-4-methyl-2-nitro-benzonitrile (873999-89-4) → 5-methoxy-4-methyl-2-nitrobenzoic acid (857599-32-7)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous NaOH

With sodium hydroxide;

DOI:10.1039/jr9530003646

Reference yield:

5-hydroxy-4-methyl-2-nitro-benzoic acid (6632-24-2) + dimethyl sulfate (77-78-1) → 5-methoxy-4-methyl-2-nitrobenzoic acid (857599-32-7)

Guidance literature:

DOI:10.1039/jr9530003646

upstream raw materials:

5-hydroxy-4-methyl-2-nitro-benzoic acid

dimethyl sulfate

3-hydroxy-4-methylbenzonitrile

5-hydroxy-4-methyl-2-nitro-benzonitrile

Downstream raw materials:

methyl 2-amino-5-methoxy-4-methylbenzoate