2-nitro-2'-phthalimidobiphenyl

Base Information

• Chemical Name: 2-nitro-2'-phthalimidobiphenyl
• CAS No.: 24838-27-5
• Molecular Formula: C₂₀H₁₂N₂O₄
• Molecular Weight: 344.326
• Mol file: 24838-27-5.mol

Synonyms:2-nitro-2'-phthalimidobiphenyl

Chemical Property of 2-nitro-2'-phthalimidobiphenyl

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-nitro-2'-phthalimidobiphenyl

There total 1 articles about 2-nitro-2'-phthalimidobiphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

2-nitrophenyl bromide (577-19-5) + 2-(2-iodophenyl)isoindoline-1,3-dione (154824-10-9) → 2-nitro-2'-phthalimidobiphenyl (24838-27-5)

Guidance literature:

With copper; at 200 ℃; for 3h;

DOI:10.1246/bcsj.67.895

Reference yield:

2-nitro-2'-phthalimidobiphenyl (24838-27-5) → benzo[c]cinnoline (230-17-1)

Guidance literature:

Multi-step reaction with 4 steps

1: aq. acetic acid, iron / acetone / 3 h / Heating

2: 1.) aq. H₂SO₄, NaNO₂, 2.) NaN₃ / dioxane / 1.) 0-5 deg C, 20 min, 2.) RT, 70 min

3: 71 percent / aq. hydrazine / methanol / 1 h / Ambient temperature

4: 23 percent / methanol / 0.75 h / Ambient temperature; Irradiation

With sodium azide; sulfuric acid; iron; hydrazine hydrate; acetic acid; sodium nitrite; In 1,4-dioxane; methanol; acetone;

DOI:10.1246/bcsj.67.895

Reference yield:

2-nitro-2'-phthalimidobiphenyl (24838-27-5) → 2-amino-2'-phthalimidobiphenyl (53290-48-5)

Guidance literature:

With iron; acetic acid; In acetone; for 3h; Yield given; Heating;

DOI:10.1246/bcsj.67.895

upstream raw materials:

2-nitrophenyl bromide

2-(2-iodophenyl)isoindoline-1,3-dione

Downstream raw materials:

2-amino-2'-phthalimidobiphenyl

benzo[c]cinnoline

4-aminocarbazole

1,1'-biphenyl-2,2'-diamine