diphenylmethyl 2-acetamido-2-deoxy-1-thio-β-D-glucopyranoside

Base Information

• Chemical Name: diphenylmethyl 2-acetamido-2-deoxy-1-thio-β-D-glucopyranoside
• CAS No.: 91288-40-3
• Molecular Formula: C₂₁H₂₅NO₅S
• Molecular Weight: 403.499
• Mol file: 91288-40-3.mol

Synonyms:diphenylmethyl 2-acetamido-2-deoxy-1-thio-β-D-glucopyranoside

Chemical Property of diphenylmethyl 2-acetamido-2-deoxy-1-thio-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diphenylmethyl 2-acetamido-2-deoxy-1-thio-β-D-glucopyranoside

There total 5 articles about diphenylmethyl 2-acetamido-2-deoxy-1-thio-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

diphenylmethyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-1-thio-β-D-glucopyranoside (91288-39-0) → diphenylmethyl 2-acetamido-2-deoxy-1-thio-β-D-glucopyranoside (91288-40-3)

Guidance literature:

With triethylamine; In methanol; water; for 6h; Ambient temperature;

DOI:10.1016/0008-6215(84)85124-1

Reference yield:

S-thiouronium 2-N-acetamido-3,4,6-tri-O-acetyl-2-deoxy-1-thio-β-D-glucopyranoside hydrochloride (51224-18-1) → diphenylmethyl 2-acetamido-2-deoxy-1-thio-β-D-glucopyranoside (91288-40-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 62 percent / potassium pyrosulfite / H₂O; CHCl₃ / 1.) 85 deg C, 2o min; 2.) rt, 0.5 h.

2: 28 percent / K₂CO₃ / acetone; H₂O / 6 h / Ambient temperature

3: 77 percent / 10percent triethylamine / methanol; H₂O / 6 h / Ambient temperature

With potassium disulphite; potassium carbonate; triethylamine; In methanol; chloroform; water; acetone;

DOI:10.1016/0008-6215(84)85124-1

Reference yield:

2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-1-thio-β-D-glucopyranose (51450-09-0) → diphenylmethyl 2-acetamido-2-deoxy-1-thio-β-D-glucopyranoside (91288-40-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 28 percent / K₂CO₃ / acetone; H₂O / 6 h / Ambient temperature

2: 77 percent / 10percent triethylamine / methanol; H₂O / 6 h / Ambient temperature

With potassium carbonate; triethylamine; In methanol; water; acetone;

DOI:10.1016/0008-6215(84)85124-1

upstream raw materials:

diphenylmethyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-1-thio-β-D-glucopyranoside

2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-1-thio-β-D-glucopyranose

S-thiouronium 2-N-acetamido-3,4,6-tri-O-acetyl-2-deoxy-1-thio-β-D-glucopyranoside hydrochloride

2-acetamido-3,4,6-tri-O-acetyl-1-carbamoyl-2-deoxy-1-thio-β-D-glucopyranose