PROLINE, 5-OXO-1-(PHENYLMETHYL)-, ETHYL ESTER

Base Information

Chemical Name:PROLINE, 5-OXO-1-(PHENYLMETHYL)-, ETHYL ESTER
CAS No.:942603-46-5
Molecular Formula:C14H17 N O3
Molecular Weight:247.29000
Hs Code.:2933790090
Mol file:942603-46-5.mol

Synonyms:Ethyl 1-benzyl-5-oxo-2-pyrrolidinecarboxylate;ethyl 1-benzyl-5-pyrrolidinone-2-carboxylate;

Suppliers and Price of PROLINE, 5-OXO-1-(PHENYLMETHYL)-, ETHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl1-benzyl-5-oxopyrrolidine-2-carboxylate 95+%
1g
$ 429.00

Chemenu
ethyl1-benzyl-5-oxopyrrolidine-2-carboxylate 95%
1g
$ 405.00

Total 7 raw suppliers

Chemical Property of PROLINE, 5-OXO-1-(PHENYLMETHYL)-, ETHYL ESTER

Chemical Property:

Boiling Point:407.6±45.0 °C(Predicted)
PKA:-2.38±0.40(Predicted)
PSA：46.61000
Density:1.184±0.06 g/cm3(Predicted)
LogP:1.67860
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

Ethyl1-benzyl-5-oxopyrrolidine-2-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of PROLINE, 5-OXO-1-(PHENYLMETHYL)-, ETHYL ESTER

There total 1 articles about PROLINE, 5-OXO-1-(PHENYLMETHYL)-, ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100-39-0
benzyl bromide

: 66183-71-9
ethyl 2-oxopyrrolidine-5-carboxylate

: 942603-46-5
ethyl 1-benzyl-5-pyrrolidinone-2-carboxylate

Guidance literature:: In tetrahydrofuran; hexane;

Reference yield: 96.0%

: 942603-46-5
ethyl 1-benzyl-5-pyrrolidinone-2-carboxylate

: 135350-26-4
1-benzyl-5-oxopyrrolidine-2-carbonyl chloride

Guidance literature:: ethyl 1-benzyl-5-pyrrolidinone-2-carboxylate; With sodium hydroxide; at 20 ℃;

With thionyl chloride; In dichloromethane; at 20 ℃; for 0.5h;
DOI:10.1016/j.tet.2007.03.084

Reference yield:

: 942603-46-5
ethyl 1-benzyl-5-pyrrolidinone-2-carboxylate

: 1,4-dibenzyl-4-(2-chloromethyl-allyl)-5-oxo-pyrrolidine-2-carboxylic acid diisopropylamide

Guidance literature:: Multi-step reaction with 4 steps

1.1: aq. NaOH / 20 °C

1.2: 96 percent / SOCl₂ / CH₂Cl₂ / 0.5 h / 20 °C

2.1: 74 percent / triethylamine / CH₂Cl₂ / 1 h / 20 °C

3.1: 33 percent / LiHMDS / -78 °C

4.1: LiHMDS / -40 °C

With sodium hydroxide; triethylamine; lithium hexamethyldisilazane; In dichloromethane;
DOI:10.1016/j.tet.2007.03.084