C₁₉H₁₈N₂O₈

Base Information

• Chemical Name: C₁₉H₁₈N₂O₈
• CAS No.: 1338699-08-3
• Molecular Formula: C₁₉H₁₈N₂O₈
• Molecular Weight: 402.361
• Mol file: 1338699-08-3.mol

Synonyms:C₁₉H₁₈N₂O₈

Chemical Property of C₁₉H₁₈N₂O₈

Chemical Property:

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Technology Process of C₁₉H₁₈N₂O₈

There total 1 articles about C₁₉H₁₈N₂O₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

C14H10N2O4 (1059698-91-7) + malonic acid dimethyl ester (108-59-8) → C19H18N2O8 (1338699-08-3) + C19H18N2O8

Guidance literature:

C₁₄H₁₀N₂O₄; With (3aR,3a’R,8aS,8a’S)-2,2’-(cyclopropane-1,1-diyl)bis(3a,8a-dihydro-8H-indeno[1,2-d]-oxazole); zinc trifluoromethanesulfonate; In dichloromethane; at -25 - 20 ℃; Inert atmosphere;

malonic acid dimethyl ester; With triethylamine; In dichloromethane; at -25 ℃; for 36h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;

DOI:10.1021/ol202405v

upstream raw materials:

C₁₄H₁₀N₂O₄

malonic acid dimethyl ester