Methyl 2-amino-4-chloro-5-iodobenzoate

Base Information

Chemical Name:Methyl 2-amino-4-chloro-5-iodobenzoate
CAS No.:199850-56-1
Molecular Formula:C8H7 Cl I N O2
Molecular Weight:311.507
Hs Code.:
DSSTox Substance ID:DTXSID00445871
Nikkaji Number:J1.266.663B
Wikidata:Q72489240
Mol file:199850-56-1.mol

Synonyms:METHYL 2-AMINO-4-CHLORO-5-IODOBENZOATE;199850-56-1;2-amino-4-chloro-5-iodo-benzoic acid methyl ester;2-amino-4-chloro-5-iodobenzoic acid methyl ester;SCHEMBL857214;DTXSID00445871;ZGCFYZJEPDVXQD-UHFFFAOYSA-N;ZHA85056;MFCD11977364;AKOS015909099;DS-7316;CS-0041075;METHYL2-AMINO-4-CHLORO-5-IODOBENZOATE;EN300-310443;A814134;Z1269118918

Suppliers and Price of Methyl 2-amino-4-chloro-5-iodobenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl2-Amino-4-chloro-5-iodobenzoate
100mg
$ 60.00

Crysdot
Methyl2-amino-4-chloro-5-iodobenzoate 95+%
5g
$ 168.00

Chemenu
methyl2-amino-4-chloro-5-iodobenzoate 95%
10g
$ 337.00

Chemenu
methyl2-amino-4-chloro-5-iodobenzoate 95%
5g
$ 196.00

Ambeed
Methyl2-amino-4-chloro-5-iodobenzoate 97%
1g
$ 50.00

Ambeed
Methyl2-amino-4-chloro-5-iodobenzoate 97%
250mg
$ 16.00

Ambeed
Methyl2-amino-4-chloro-5-iodobenzoate 97%
5g
$ 150.00

Ambeed
Methyl2-amino-4-chloro-5-iodobenzoate 97%
10g
$ 278.00

Alichem
Methyl2-amino-4-chloro-5-iodobenzoate
25g
$ 757.05

Alichem
Methyl2-amino-4-chloro-5-iodobenzoate
10g
$ 352.80

Total 11 raw suppliers

Chemical Property of Methyl 2-amino-4-chloro-5-iodobenzoate

Chemical Property:

Boiling Point:369.2±42.0 °C(Predicted)
PKA:0.99±0.10(Predicted)
PSA：52.32000
Density:1.903
LogP:2.89460
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:310.92100
Heavy Atom Count:13
Complexity:203

Purity/Quality:

97% ^*data from raw suppliers

Methyl2-Amino-4-chloro-5-iodobenzoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC(=C(C=C1N)Cl)I

Technology Process of Methyl 2-amino-4-chloro-5-iodobenzoate

There total 4 articles about Methyl 2-amino-4-chloro-5-iodobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 5900-58-3
2-amino-4-chloro-benzoic acid methyl ester

: 199850-56-1
methyl 2-amino-4-chloro-5-iodobenzoate

Guidance literature:: With iodine; silver sulfate; In ethanol; at 20 ℃; for 0.75h;
DOI:10.1002/jlcr.733

Reference yield:

: 147778-06-1
2-acetylamino-4-chlorobenzoic acid methyl ester

: 199850-56-1
methyl 2-amino-4-chloro-5-iodobenzoate

Guidance literature:: With iodine; silver trifluoromethanesulfonate; In chloroform;

Reference yield:

: 717879-44-2
methyl 2-amino-4-tert-butylbenzoate

: 199850-56-1
methyl 2-amino-4-chloro-5-iodobenzoate

Guidance literature:: Multi-step reaction with 3 steps

1: iodine; silver sulfate / ethanol

2: tri-n-butyl-tin hydride; bis-triphenylphosphine-palladium(II) chloride / 1,4-dioxane / 18 h / 85 °C

3: iodine; silver sulfate / ethanol

With bis-triphenylphosphine-palladium(II) chloride; iodine; tri-n-butyl-tin hydride; silver sulfate; In 1,4-dioxane; ethanol;
DOI:10.1002/cmdc.201600467