4-{[(3aR,5aR,5bR,7aR,9S,11aR,11bR,13aS)-3a-[{[(4-chlorophenyl)methyl]amino}acetyl]-5a,5b,8,8,11a-pentamethyl-1-(1-methylethyl)-2-oxo-3,3a,4,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a-octadecahydro-2H-cyclopenta[a]chrysen-9-yl]oxy}-2,2-dimethyl-4-oxo-butanoic acid

Base Information

Chemical Name:4-{[(3aR,5aR,5bR,7aR,9S,11aR,11bR,13aS)-3a-[{[(4-chlorophenyl)methyl]amino}acetyl]-5a,5b,8,8,11a-pentamethyl-1-(1-methylethyl)-2-oxo-3,3a,4,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a-octadecahydro-2H-cyclopenta[a]chrysen-9-yl]oxy}-2,2-dimethyl-4-oxo-butanoic acid
CAS No.:1326312-12-2
Molecular Formula:C₄₄H₆₂ClNO₆
Molecular Weight:736.432
Hs Code.:

4-{[(3aR,5aR,5bR,7aR,9S,11aR,11bR,13aS)-3a-[{[(4-chlorophenyl)methyl]amino}acetyl]-5a,5b,8,8,11a-pentamethyl-1-(1-methylethyl)-2-oxo-3,3a,4,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a-octadecahydro-2H-cyclopenta[a]chrysen-9-yl]oxy}-2,2-dimethyl-4-oxo-butanoic acid

Synonyms:4-{[(3aR,5aR,5bR,7aR,9S,11aR,11bR,13aS)-3a-[{[(4-chlorophenyl)methyl]amino}acetyl]-5a,5b,8,8,11a-pentamethyl-1-(1-methylethyl)-2-oxo-3,3a,4,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a-octadecahydro-2H-cyclopenta[a]chrysen-9-yl]oxy}-2,2-dimethyl-4-oxo-butanoic acid

Suppliers and Price of 4-{[(3aR,5aR,5bR,7aR,9S,11aR,11bR,13aS)-3a-[{[(4-chlorophenyl)methyl]amino}acetyl]-5a,5b,8,8,11a-pentamethyl-1-(1-methylethyl)-2-oxo-3,3a,4,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a-octadecahydro-2H-cyclopenta[a]chrysen-9-yl]oxy}-2,2-dimethyl-4-oxo-butanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-{[(3aR,5aR,5bR,7aR,9S,11aR,11bR,13aS)-3a-[{[(4-chlorophenyl)methyl]amino}acetyl]-5a,5b,8,8,11a-pentamethyl-1-(1-methylethyl)-2-oxo-3,3a,4,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a-octadecahydro-2H-cyclopenta[a]chrysen-9-yl]oxy}-2,2-dimethyl-4-oxo-butanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-{[(3aR,5aR,5bR,7aR,9S,11aR,11bR,13aS)-3a-[{[(4-chlorophenyl)methyl]amino}acetyl]-5a,5b,8,8,11a-pentamethyl-1-(1-methylethyl)-2-oxo-3,3a,4,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a-octadecahydro-2H-cyclopenta[a]chrysen-9-yl]oxy}-2,2-dimethyl-4-oxo-butanoic acid

There total 6 articles about 4-{[(3aR,5aR,5bR,7aR,9S,11aR,11bR,13aS)-3a-[{[(4-chlorophenyl)methyl]amino}acetyl]-5a,5b,8,8,11a-pentamethyl-1-(1-methylethyl)-2-oxo-3,3a,4,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a-octadecahydro-2H-cyclopenta[a]chrysen-9-yl]oxy}-2,2-dimethyl-4-oxo-butanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.5%

: 1326312-11-1
C₄₉H₇₀ClNO₈

: 1326312-12-2
4-{[(3aR,5aR,5bR,7aR,9S,11aR,11bR,13aS)-3a-[{[(4-chlorophenyl)methyl]amino}acetyl]-5a,5b,8,8,11a-pentamethyl-1-(1-methylethyl)-2-oxo-3,3a,4,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a-octadecahydro-2H-cyclopenta[a]chrysen-9-yl]oxy}-2,2-dimethyl-4-oxo-butanoic acid

Guidance literature:: C₄₉H₇₀ClNO₈; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h;

With sodium hydrogencarbonate; In dichloromethane; water;

Reference yield:

: 1326312-06-4
C₄₀H₅₈ClNO₄

: 1326312-12-2
4-{[(3aR,5aR,5bR,7aR,9S,11aR,11bR,13aS)-3a-[{[(4-chlorophenyl)methyl]amino}acetyl]-5a,5b,8,8,11a-pentamethyl-1-(1-methylethyl)-2-oxo-3,3a,4,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a-octadecahydro-2H-cyclopenta[a]chrysen-9-yl]oxy}-2,2-dimethyl-4-oxo-butanoic acid

Guidance literature:: Multi-step reaction with 6 steps

1: triethylamine / 20 °C

2: silica gel; pyridinium chlorochromate / dichloromethane / 8 h / 20 °C

3: hydrogenchloride; water / 1,4-dioxane / 20 °C

4: triethylamine / dichloromethane / 1 h / 20 °C

5: dmap; pyridine / 80 °C

6: trifluoroacetic acid / dichloromethane / 1 h / 20 °C

With pyridine; hydrogenchloride; dmap; water; silica gel; triethylamine; pyridinium chlorochromate; trifluoroacetic acid; In 1,4-dioxane; dichloromethane;

Reference yield:

: 1326312-07-5
(3aR,5aR,5bR,7aR,9S,11aR,11bR,13aS)-3a-(2-((tert-butoxycarbonyl)(4-chlorobenzyl)amino)-1-hydroxyethyl)-1-isopropyl-5a,5b,8,8,11a-pentamethyl-2-oxo-3,3a,4,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a-octadecahydro-2H-cyclopenta[a]chrysen-9-yl acetate

: 1326312-12-2
4-{[(3aR,5aR,5bR,7aR,9S,11aR,11bR,13aS)-3a-[{[(4-chlorophenyl)methyl]amino}acetyl]-5a,5b,8,8,11a-pentamethyl-1-(1-methylethyl)-2-oxo-3,3a,4,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a-octadecahydro-2H-cyclopenta[a]chrysen-9-yl]oxy}-2,2-dimethyl-4-oxo-butanoic acid

Guidance literature:: Multi-step reaction with 5 steps

1: silica gel; pyridinium chlorochromate / dichloromethane / 8 h / 20 °C

2: hydrogenchloride; water / 1,4-dioxane / 20 °C

3: triethylamine / dichloromethane / 1 h / 20 °C

4: dmap; pyridine / 80 °C

5: trifluoroacetic acid / dichloromethane / 1 h / 20 °C

With pyridine; hydrogenchloride; dmap; water; silica gel; triethylamine; pyridinium chlorochromate; trifluoroacetic acid; In 1,4-dioxane; dichloromethane;