4-CHLORO-3-IODOANILINE

Base Information

• Chemical Name: 4-CHLORO-3-IODOANILINE
• CAS No.: 573764-31-5
• Molecular Formula: C6H5ClIN
• Molecular Weight: 253.47
• Hs Code.: 2921420090
• Mol file: 573764-31-5.mol

Synonyms:4-Chloro-3-iodoaniline;

Chemical Property of 4-CHLORO-3-IODOANILINE

Chemical Property:

• Melting Point: 70 °C
• Boiling Point: 322.297 °C at 760 mmHg
• PKA: 3.00±0.10(Predicted)
• Flash Point: 148.72 °C
• PSA: 26.02000
• Density: 2.016 g/cm³
• LogP: 3.10800
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Chloro-3-iodoaniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-CHLORO-3-IODOANILINE

There total 8 articles about 4-CHLORO-3-IODOANILINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

1-chloro-2-iodo-4-nitrobenzene (74534-15-9) → 3-iodo-4-chloroaniline (573764-31-5)

Guidance literature:

With iron; ammonium chloride; In ethanol; water; at 75 ℃; for 3h;

Reference yield:

4-chloro-aniline (106-47-8) → p-chloro-o-iodoaniline (63069-48-7) + 3-iodo-4-chloroaniline (573764-31-5)

Guidance literature:

With iodine; silica gel; In hexane; at 28 ℃;

Reference yield:

aniline (62-53-3) → p-chloro-o-iodoaniline (63069-48-7) + 3-iodo-4-chloroaniline (573764-31-5)

Guidance literature:

Multi-step reaction with 2 steps

1: ; chlorine / 1 h / 25 °C

2: iodine; silica gel / hexane / 28 °C

With iodine; silica gel; chlorine; In hexane;

upstream raw materials:

1-chloro-2-iodo-3-nitrobenzene

1-chloro-2-iodo-4-nitrobenzene

iron

H₂NC₆H₃(Cl)NO₂

Downstream raw materials:

ethyl 7-(3-chloro-4-(4-chloro-3-(pyridin-2-yl)phenylcarbamoyl)phenyl sulfonamido)heptanoate

ethyl 2-(3-chloro-4-(4-chloro-3-(pyridin-2-yl)phenylcarbamoyl)phenyl sulfonamido)pyrimidine-5-carboxylate

4-chloro-3-(pyridin-2-yl)benzeneamine

tert-butyl 4-((3-chloro-4-(4-chloro-3-(pyridin-2-yl)phenylcarbamoyl)phenyl sulfonamido)methyl)piperidine-1-carboxylate