ethyl 2-(4,6-bis(4-(trifluoromethoxy)phenethoxy)pyrimidin-2-ylthio)hexanoate

Base Information

Chemical Name:ethyl 2-(4,6-bis(4-(trifluoromethoxy)phenethoxy)pyrimidin-2-ylthio)hexanoate
CAS No.:1231733-97-3
Molecular Formula:C₃₀H₃₂F₆N₂O₆S
Molecular Weight:662.65
Hs Code.:

Synonyms:ethyl 2-(4,6-bis(4-(trifluoromethoxy)phenethoxy)pyrimidin-2-ylthio)hexanoate

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Chemical Property of ethyl 2-(4,6-bis(4-(trifluoromethoxy)phenethoxy)pyrimidin-2-ylthio)hexanoate

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Technology Process of ethyl 2-(4,6-bis(4-(trifluoromethoxy)phenethoxy)pyrimidin-2-ylthio)hexanoate

There total 1 articles about ethyl 2-(4,6-bis(4-(trifluoromethoxy)phenethoxy)pyrimidin-2-ylthio)hexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.1%

: 916482-23-0
ethyl 2-((4,6-dihydroxypyrimidin-2-yl)thio)hexanoate

: 196811-90-2
2‐[4‐(trifluoromethoxy)phenyl]ethanol

: 1231733-97-3
ethyl 2-(4,6-bis(4-(trifluoromethoxy)phenethoxy)pyrimidin-2-ylthio)hexanoate

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 20 ℃; Inert atmosphere; Cooling with ice;
DOI:10.1021/jm1003073

Reference yield: 97.0%

: 1231733-97-3
ethyl 2-(4,6-bis(4-(trifluoromethoxy)phenethoxy)pyrimidin-2-ylthio)hexanoate

: 1231733-75-7
2-(4,6-bis(4-(trifluoromethoxy)phenethoxy)pyrimidin-2-ylthio)hexanoic acid

Guidance literature:: ethyl 2-(4,6-bis(4-(trifluoromethoxy)phenethoxy)pyrimidin-2-ylthio)hexanoate; With water; lithium hydroxide; In tetrahydrofuran; methanol; at 25 - 50 ℃; for 2h;

With hydrogenchloride; In water;
DOI:10.1021/jm1003073