(S)-2-cyano-1-(4-{2-[N-tert-butoxycarbonyl-N-(2-hydroxy-3-phenoxypropyl)amino]ethyl}phenyl)-3-phenylguanidine

Base Information

Chemical Name:(S)-2-cyano-1-(4-{2-[N-tert-butoxycarbonyl-N-(2-hydroxy-3-phenoxypropyl)amino]ethyl}phenyl)-3-phenylguanidine
CAS No.:209740-90-9
Molecular Formula:C₃₀H₃₅N₅O₄
Molecular Weight:529.639
Hs Code.:

Synonyms:(S)-2-cyano-1-(4-{2-[N-tert-butoxycarbonyl-N-(2-hydroxy-3-phenoxypropyl)amino]ethyl}phenyl)-3-phenylguanidine

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Chemical Property of (S)-2-cyano-1-(4-{2-[N-tert-butoxycarbonyl-N-(2-hydroxy-3-phenoxypropyl)amino]ethyl}phenyl)-3-phenylguanidine

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Technology Process of (S)-2-cyano-1-(4-{2-[N-tert-butoxycarbonyl-N-(2-hydroxy-3-phenoxypropyl)amino]ethyl}phenyl)-3-phenylguanidine

There total 1 articles about (S)-2-cyano-1-(4-{2-[N-tert-butoxycarbonyl-N-(2-hydroxy-3-phenoxypropyl)amino]ethyl}phenyl)-3-phenylguanidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

: 420-04-2
CYANAMID

: 202740-29-2
(S)-1-(4-{2-[N-tert-butoxycarbonyl-N-(2-hydroxy-3-phenoxypropyl)amino]ethyl}phenyl)-3-phenylthiourea

: 209740-90-9
(S)-2-cyano-1-(4-{2-[N-tert-butoxycarbonyl-N-(2-hydroxy-3-phenoxypropyl)amino]ethyl}phenyl)-3-phenylguanidine

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 50 ℃; for 20h;
DOI:10.1016/j.bmc.2009.06.031

Reference yield: 37.0%

: 209740-90-9
(S)-2-cyano-1-(4-{2-[N-tert-butoxycarbonyl-N-(2-hydroxy-3-phenoxypropyl)amino]ethyl}phenyl)-3-phenylguanidine

: 209740-96-5
(S)-2-cyano-1-(4-{2-[(2-hydroxy-3-phenoxypropyl)amino]ethyl}phenyl)-3-phenylguanidine hydrochloride

Guidance literature:: (S)-2-cyano-1-(4-{2-[N-tert-butoxycarbonyl-N-(2-hydroxy-3-phenoxypropyl)amino]ethyl}phenyl)-3-phenylguanidine; With trifluoroacetic acid; at 20 ℃; for 0.0833333h;

With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 0.5h;
DOI:10.1016/j.bmc.2009.06.031