2-Chloro-5-(4-methylphenyl)pyrimidine

Base Information

Chemical Name:2-Chloro-5-(4-methylphenyl)pyrimidine
CAS No.:27956-37-2
Molecular Formula:C11H9 Cl N2
Molecular Weight:204.659
Hs Code.:
DSSTox Substance ID:DTXSID001286063
Nikkaji Number:J2.625.464G
Mol file:27956-37-2.mol

Synonyms:27956-37-2;2-chloro-5-(4-methylphenyl)pyrimidine;Pyrimidine, 2-chloro-5-(4-methylphenyl)-;2-Chloro-5-(4-methylphenyl)-pyrimidine;SCHEMBL6407267;AXBSAMHKWMWOKP-UHFFFAOYSA-N;DTXSID001286063

Suppliers and Price of 2-Chloro-5-(4-methylphenyl)pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-Chloro-5-(4-methylphenyl)pyrimidine

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:204.0454260
Heavy Atom Count:14
Complexity:170

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=CN=C(N=C2)Cl

Technology Process of 2-Chloro-5-(4-methylphenyl)pyrimidine

There total 9 articles about 2-Chloro-5-(4-methylphenyl)pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 5720-05-8
4-methylphenylboronic acid

: 32779-36-5
5-Bromo-2-chloropyrimidine

: 27956-37-2
2-chloro-5-(4-methyl phenyl)pyrimidine

Guidance literature:: With potassium fluoride; palladium diacetate; In methanol; at 120 ℃; for 0.333333h; microwave irradiation;
DOI:10.1002/jhet.5570450420

Reference yield: 79.5%

: 27956-37-2
2-chloro-5-(4-methyl phenyl)pyrimidine

Guidance literature:: With tetrakis-(triphenylphosphine)-palladium; potassium carbonate; In toluene; at 100 ℃; for 3.5h; Inert atmosphere;

Reference yield: 72.0%

: 31614-66-1
tributyl(p-tolyl)stannane

: 32779-36-5
5-Bromo-2-chloropyrimidine

: 27956-37-2
2-chloro-5-(4-methyl phenyl)pyrimidine

Guidance literature:: With palladium diacetate; cesium fluoride; tricyclohexylphosphine; In neat (no solvent); at 110 ℃; for 24h; under 760.051 Torr; Sealed tube;
DOI:10.1002/ejoc.201701463