1-tert-butyloxycarbonyl-4-(2-(3-fluorophenyl)ethyl)-4-hydroxypiperidine

Base Information

Chemical Name:1-tert-butyloxycarbonyl-4-(2-(3-fluorophenyl)ethyl)-4-hydroxypiperidine
CAS No.:211108-41-7
Molecular Formula:C₁₈H₂₆FNO₃
Molecular Weight:323.408
Hs Code.:

Synonyms:1-tert-butyloxycarbonyl-4-(2-(3-fluorophenyl)ethyl)-4-hydroxypiperidine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-tert-butyloxycarbonyl-4-(2-(3-fluorophenyl)ethyl)-4-hydroxypiperidine

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Technology Process of 1-tert-butyloxycarbonyl-4-(2-(3-fluorophenyl)ethyl)-4-hydroxypiperidine

There total 2 articles about 1-tert-butyloxycarbonyl-4-(2-(3-fluorophenyl)ethyl)-4-hydroxypiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 456-41-7
1-(Bromomethyl)-3-fluorobenzene

: 147804-30-6
1-oxa-6-aza-spiro-[2.5]octane-6-caboxylic acid tert-butyl ester

: 211108-41-7
1-tert-butyloxycarbonyl-4-(2-(3-fluorophenyl)ethyl)-4-hydroxypiperidine

Guidance literature:: With magnesium; Multistep reaction; 1.) Et₂O, 2.) Et₂O, -30 deg C;
DOI:10.1021/jm980204e

Reference yield:

: 211108-41-7
1-tert-butyloxycarbonyl-4-(2-(3-fluorophenyl)ethyl)-4-hydroxypiperidine

Guidance literature:

Reference yield:

: 211108-41-7
1-tert-butyloxycarbonyl-4-(2-(3-fluorophenyl)ethyl)-4-hydroxypiperidine

: 4-[2-(3-fluoro-phenyl)-ethyl]-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester

: 211108-42-8
1-tert-butyloxycarbonyl-4-fluoro-4-(2-(3-fluorophenyl)ethyl)piperidine

Guidance literature:: With diethylamino-sulfur trifluoride; In dichloromethane; at -78 - 0 ℃; Title compound not separated from byproducts;
DOI:10.1021/jm980204e