butyl(2-phenylethyl)amine

Base Information

• Chemical Name: butyl(2-phenylethyl)amine
• CAS No.: 23068-45-3
• Molecular Formula: C₁₂H₁₉N
• Molecular Weight: 177.29
• Mol file: 23068-45-3.mol

Synonyms:N-Butyl-2-phenylethylamine

Chemical Property of butyl(2-phenylethyl)amine

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

BUTYL(2-PHENYLETHYL)AMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of butyl(2-phenylethyl)amine

There total 24 articles about butyl(2-phenylethyl)amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

butyraldehyde (123-72-8) + phenethylamine (64-04-0) → N-Butyl-2-phenylethylamine (23068-45-3)

Guidance literature:

With hydrogen; Pt/Al₂O₃; In methanol; under 67229.2 Torr; Ambient temperature;

DOI:10.1002/recl.19931121007

Reference yield: 89.0%

1-bromo-butane (109-65-9) + phenethylamine (64-04-0) → N-Butyl-2-phenylethylamine (23068-45-3) + N-butyl-N-phenethylbutan-1-amine (5779-51-1)

Guidance literature:

With cesium hydroxide; 4 A molecular sieve; In N,N-dimethyl-formamide; at 23 ℃; for 21h;

DOI:10.1021/ol9910417

Reference yield: 87.0%

phenylacetonitrile (140-29-4) + N-butylamine (109-73-9,85404-21-3) → N-Butyl-2-phenylethylamine (23068-45-3) + diphenethylamine (6308-98-1)

Guidance literature:

With 3 % platinum on carbon; hydrogen; In toluene; at 105 ℃; under 4500.45 Torr; Flow reactor;

DOI:10.1039/c2cy20431b

upstream raw materials:

N-butyl-2-phenylethanethioamide

butyraldehyde

phenethylamine

butan-1-ol

Downstream raw materials:

1-Butyl-1-phenaethyl-biuret

N-ethyl-N-pentyl-2-phenethylamine

N-butyl-N-phenethylacetamide

N-butyl-N-phenethylbutan-1-amine

Refernces

• 1、 Yao, Wubing,Fang, Huaquan,He, Qiaoxing,Peng, Dongjie,Liu, Guixia,Huang, Zheng. "A BEt3-Base Catalyst for Amide Reduction with Silane". . p. 6084 - 6093. Retrieved 2019/05/24.
• 2、 Popov, Yu. V.,Mokhov,Shcherbakova. "Colloid and nanosized catalysts in organic synthesis: XIV. Reductive amination and amidation of carbonitriles catalyzed by nickel nanoparticles". . p. 798 - 805. Retrieved 2016/06/13.