(S)-4,4'-DiMethoxy-7,7'-dihydroxy-1,1'-spirobiindane

Base Information

Chemical Name:(S)-4,4'-DiMethoxy-7,7'-dihydroxy-1,1'-spirobiindane
CAS No.:636601-30-4
Molecular Formula:C₁₉H₂₀O₄
Molecular Weight:312.365
Hs Code.:
Mol file:636601-30-4.mol

Synonyms:(S)-4,4'-Dimethoxy-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol;

Suppliers and Price of (S)-4,4'-DiMethoxy-7,7'-dihydroxy-1,1'-spirobiindane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-4,4'-Dimethoxy-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol 95+%
1g
$ 1081.00

Chemenu
(S)-4,4''-dimethoxy-2,2'',3,3''-tetrahydro-1,1''-spirobi[indene]-7,7''-diol 95%
1g
$ 1018.00

Total 5 raw suppliers

Chemical Property of (S)-4,4'-DiMethoxy-7,7'-dihydroxy-1,1'-spirobiindane

Chemical Property:

PSA：58.92000
LogP:3.29350
Storage Temp.:2-8°C

Purity/Quality:

99% ^*data from raw suppliers

(S)-4,4'-Dimethoxy-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-4,4'-DiMethoxy-7,7'-dihydroxy-1,1'-spirobiindane

There total 3 articles about (S)-4,4'-DiMethoxy-7,7'-dihydroxy-1,1'-spirobiindane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 124-41-4
sodium methylate

: 636601-27-9,681481-91-4,681481-94-7
(S)-4,4'-dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol

: 636601-30-4
(S)-4,4'-dimethoxy-7,7'-dihydroxy-1,1'-spirobiindane

Guidance literature:: With copper(l) chloride; In N,N-dimethyl-formamide; at 120 ℃; for 12h;
DOI:10.1016/j.tetasy.2003.08.017

Reference yield:

: 223137-81-3,636601-25-7
(S)-7,7'-dimethoxy-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]

: 636601-30-4
(S)-4,4'-dimethoxy-7,7'-dihydroxy-1,1'-spirobiindane

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / NaBr; glacial acetic acid; H₂O₂ / 24 h / 20 °C

2: 92 percent / BBr₃ / CH₂Cl₂ / 12 h / -78 - 20 °C

3: 70 percent / CuCl / dimethylformamide / 12 h / 120 °C

With dihydrogen peroxide; boron tribromide; acetic acid; sodium bromide; copper(l) chloride; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.tetasy.2003.08.017

Reference yield:

: 223137-76-6,636601-26-8
(S)-4,4'-dibromo-7,7'-dimethoxy-1,1'-spirobiindane

: 636601-30-4
(S)-4,4'-dimethoxy-7,7'-dihydroxy-1,1'-spirobiindane

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / BBr₃ / CH₂Cl₂ / 12 h / -78 - 20 °C

2: 70 percent / CuCl / dimethylformamide / 12 h / 120 °C

With boron tribromide; copper(l) chloride; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.tetasy.2003.08.017