Pgd2-IN-1

Base Information

Chemical Name:Pgd2-IN-1
CAS No.:885066-67-1
Molecular Formula:C₂₃H₂₃Cl₂N₃O₃
Molecular Weight:460.36
Hs Code.:
UNII:JXZ83H2X06
ChEMBL ID:CHEMBL1644245
Mol file:885066-67-1.mol

Synonyms:PGD2-IN-1;885066-67-1;PGD2-inhibitor;MDK66671;JXZ83H2X06;CHEMBL1644245;MDK-66671;2-(3-(6-((2,4-dichlorophenethyl)amino)-2-methoxypyrimidin-4-yl)phenyl)-2-methylpropanoic acid;2-(3-(6-((2-(2,4-Dichlorophenyl)ethyl)amino)-2-methoxypyrimidin-4-yl)phenyl)-2-methylpropionic acid;Benzeneacetic acid,3-[6-[[2-(2,4-dichlorophenyl)ethyl]amino]-2-methoxy-4-pyrimidinyl]-a,a-dimethyl-;UNII-JXZ83H2X06;SCHEMBL2563601;prostaglandin D2PGD2) inhibitor;FJKKCRCBBAXLQZ-UHFFFAOYSA-N;BCP20749;BDBM50417747;AKOS032960433;CS-6338;MS-28432;HY-101430;N16819;A903614;MDK-66671 MDK 66671;2-(3-{6-[2-(2,4-dichloro-phenyl)-ethylamino]-2-methoxy-pyrimidin-4-yl}-phenyl)-2-methyl-propionic acid;2-(3-{6-[2-(2,4-dichloro-phenyl)-ethylamino]-2-methoxy-pyrimidin-4-yl}-phenyl)-2-methylpropionic acid;2-[3-(6-{[2-(2,4-dichlorophenyl)ethyl]amino}-2-methoxypyrimidin-4-yl)phenyl]-2-methylpropanoic acid;2-[3-[6-[2-(2,4-dichlorophenyl)ethylamino]-2-methoxypyrimidin-4-yl]phenyl]-2-methylpropanoic acid;BENZENEACETIC ACID, 3-(6-((2-(2,4-DICHLOROPHENYL)ETHYL)AMINO)-2-METHOXY-4-PYRIMIDINYL)-.ALPHA.,.ALPHA.-DIMETHYL-;Benzeneacetic acid, 3-(6-((2-(2,4-dichlorophenyl)ethyl)amino)-2-methoxy-4-pyrimidinyl)-alpha,alpha-dimethyl-

Suppliers and Price of Pgd2-IN-1

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
prostaglandinD2（PGD2)inhibitor >98%
25 mg
$ 450.00

DC Chemicals
prostaglandinD2（PGD2)inhibitor >98%
10 mg
$ 300.00

Total 8 raw suppliers

Chemical Property of Pgd2-IN-1

Chemical Property:

Boiling Point:682.1±65.0 °C(Predicted)
PKA:4.09±0.10(Predicted)
Density:1.326±0.06 g/cm3(Predicted)
XLogP3:6.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:459.1116470
Heavy Atom Count:31
Complexity:594

Purity/Quality:

97% ^*data from raw suppliers

prostaglandinD2（PGD2)inhibitor >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C1=CC=CC(=C1)C2=CC(=NC(=N2)OC)NCCC3=C(C=C(C=C3)Cl)Cl)C(=O)O

Technology Process of Pgd2-IN-1

There total 6 articles about Pgd2-IN-1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 885068-00-8
2-(3-boronophenyl)-2-methylpropanoic acid

: 1016644-41-9
(6-chloro-2-methoxy-pyrimidin-4-yl)-[2-(2,4-dichloro-phenyl)-ethyl]-amine

: 885066-67-1
2-(3-{6-[2-(2,4-dichloro-phenyl)-ethylamino]-2-methoxy-pyrimidin-4-yl}-phenyl)-2-methyl-propionic acid

Guidance literature:: 2-(3-boronophenyl)-2-methylpropanoic acid; (6-chloro-2-methoxy-pyrimidin-4-yl)-[2-(2,4-dichloro-phenyl)-ethyl]-amine; With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In water; acetonitrile; at 130 ℃; for 0.5h; Microwave irradiation;

With hydrogenchloride; water; In acetonitrile; pH=7;