52516-13-9

Basic information

• Product Name: 1-(2,4-DICHLORO-PHENYL)-ETHYLAMINE
• Synonyms: 2-(2,4-Dichlorophenyl)ethanamine;1-AMINO-1-(2,4-DICHLOROPHENYL)ETHANE;1-AMINO-2-(2,4-DICHLOROPHENYL)ETHANE;1-(2',4'-DICHLOROPHENYL)ETHYLAMINE;1-(2,4-DICHLORO-PHENYL)-ETHYLAMINE;1-(2-AMINOETHYL)-2,4-DICHLOROBENZENE;2,4-DICHLOROPHENETHYLAMINE;2,4-DICHLORO-ALPHA-PHENETHYLAMINE
• CAS NO: 52516-13-9
• Molecular Formula: C₈H₉Cl₂N
• Molecular Weight: 190.07
• Product Categories: Chiral Compound;Amines;C8;Nitrogen Compounds
• Mol File: 52516-13-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 75-76 °C0.04 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: Clear colorless to yellow/Liquid
• Density: 1.26 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0155mmHg at 25°C
• Refractive Index: n20/D 1.5651(lit.)
• PKA: 9.21±0.10(Predicted)
• CAS DataBase Reference: 1-(2,4-DICHLORO-PHENYL)-ETHYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,4-DICHLORO-PHENYL)-ETHYLAMINE(52516-13-9)
• EPA Substance Registry System: 1-(2,4-DICHLORO-PHENYL)-ETHYLAMINE(52516-13-9)

Safety Data

• Hazard Codes: Xi,T
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• HazardClass: IRRITANT, TOXIC
• Hazardous Substances Data: 52516-13-9(Hazardous Substances Data)

Usage

Chemical Properties

clear colorless to yellow liquid

Uses

2,4-Dichlorophenethylamine may be used in the synthesis of cis-(L-Arginyl)amino-N-(2,4-dichlorophenylmethyl)-L-proline 2,4-dichlorophenethylamide. It may be used in the synthesis of various N-alkylglycine.

InChI:InChI=1/C8H9Cl2N/c1-5(11)7-3-2-6(9)4-8(7)10/h2-5H,11H2,1H3

Upstream product

• 1403029-66-2 2,4-dichlorophenylethylcarbamic acid methyl ester 
• 874-42-0 2,4-dichlorobenzaldeyhde 
• 34209-97-7 2,4-dichloro-1-(2-nitrovinyl)benzene 
• 6306-60-1 2,4-Dichlorophenylacetonitrile 

Downstream Products

• 99860-46-5 N-(2,4-dichloro-phenethyl)-β-alanine nitrile 
• 355381-57-6 [2-(2,4-Dichloro-phenyl)-ethyl]-(4-nitro-benzyl)-amine 
• 6515-64-6 3-(2,4-dichloro-phenethyl)-5-(2-diethylamino-ethyl)-[1,3,5]thiadiazinane-2-thione 
• 1021003-92-8 N-<2-(2,4-dichlorophenyl)ethyl>glycine ethyl ester 
• 221656-36-6 N,N-bis(benzotriazol-1-ylmethyl)-2,4-dichloro-β-phenylethylamine 
• 34164-20-0 (2R,S)-2-chloro-N-(2,4-dichlorophenethyl)propanamide 
• 870998-03-1 N-[2-(2,4-dichlorophenyl)ethyl]-4-fluoro-3-nitrobenzamide 
• 866523-71-9 5-(2-methylsulfanyl-pyrimidin-4-yl)-thiophene-2-carboxylic acid [2-(2,4-dichloro-phenyl)-ethyl]-amide 
• 1009102-35-5 N-(2,4-dichlorophenethyl)-2-fluoro-4-hydroxybenzamide 

Relevant articles and documents

Preparation method 5,7 - dichloro -1, 2, 3 and 4 - tetrahydroisoquinoline

The invention provides a preparation method of 5, 7 - dichloro -1, 2, 3 and 4 - tetrahydroisoquinoline, which comprises the following steps: reducing 2, 4 - dichlorobenzene acetonitrile by first reducing agent to generate 2 and 4 - dichlorophenylethylamin

Synthesis and antioxidant characteristic of novel thiazolidinone derivatives

A series of novel thiazolidinone derivatives have been synthesized by solventless condensation of N-alkylamines with arylaldehydes at room temperature followed by a microwave assisted solventless addition of thioglycollic acid to the resultant imines. The synthesized compounds are characterized by 1H NMR, 13C NMR, MS and X-ray techniques and one of the synthesized thiazolidinones has been evaluated for its antioxidant property.

2-aminobenzoxazole derivatives and combinatorial libraries thereof

The present invention relates to novel 2-aminobenzoxazole derivative compounds of the following formula: wherein R1 to R4 and Z have the meanings provided herein. The invention further relates to combinatorial libraries containing two or more such compounds, as well as methods of preparing 2-aminobenzoxazole derivative compounds.