4-Propylpyridin-2-amine

Base Information

• Chemical Name: 4-Propylpyridin-2-amine
• CAS No.: 61702-15-6
• Molecular Formula: C8H12N2
• Molecular Weight: 136.197
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID00427455
• Nikkaji Number: J1.385.269C
• Wikidata: Q82240118
• ChEMBL ID: CHEMBL59235
• Mol file: 61702-15-6.mol

Synonyms:4-propylpyridin-2-amine;61702-15-6;4-Propyl-pyridin-2-ylamine;2-Amino-4-propylpyridine;4-Propylpyridin-2-ylamine;CHEMBL59235;2-Pyridinamine,4-propyl-;4-propyl-2-pyridinamine;4-propylpyridine-2-amine;2-Amino-4-n-propylpyridine;2--Amino-4-n-propylpyridine;SCHEMBL105611;AMY2565;DTXSID00427455;CGGOAYCJQTWSOI-UHFFFAOYSA-N;BDBM50091812;AKOS013445809;2-AMINO-4-(N-PROPYL)PYRIDINE;AB03633;CS-0326861;FT-0640775;A833379

Chemical Property of 4-Propylpyridin-2-amine

Chemical Property:

• Vapor Pressure: 0.0146mmHg at 25°C
• Refractive Index: 1.549
• Boiling Point: 257.4 °C at 760 mmHg
• Flash Point: 133.2 °C
• PSA: 38.91000
• Density: 1.014 g/cm³
• LogP: 2.19750
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 136.100048391
• Heavy Atom Count: 10
• Complexity: 93.3

Purity/Quality:

99% ^*data from raw suppliers

4-Propyl-pyridin-2-ylamine 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCC1=CC(=NC=C1)N

Technology Process of 4-Propylpyridin-2-amine

There total 7 articles about 4-Propylpyridin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-(4-methoxybenzyl)-4-propylpyridin-2-amine → 4-propylpyridin-2-amine (61702-15-6)

Guidance literature:

With trifluoroacetic acid;

Reference yield: 85.0%

4-propylpicolinamide → 4-propylpyridin-2-amine (61702-15-6)

Guidance literature:

With sodium hypochlorite; sodium hydroxide; In water; at 50 ℃; for 1h;

Reference yield: 51.0%

4-n-propylpyridine (1122-81-2) → 4-propylpyridin-2-amine (61702-15-6)

Guidance literature:

With sodium amide; In toluene; at 140 ℃; for 48h;

upstream raw materials:

4-n-propylpyridine

4-propylpyridine-1-oxide

4-n-propyl-2-pyridinecarbonitrile

2-chloro-4-propylpyridine

Downstream raw materials:

(S)-4-(8-methyl-3-(piperidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(4-propylpyridin-2-yl)benzamide

(S)-benzyl 2-(8-methyl-1-(4-(4-propylpyridin-2-ylcarbamoyl)phenyl)imidazo[1 ,5-a]pyrazin-3-yl)piperidine-1-carboxylate

Refernces

• 1、 -. "INHIBITORS OF BRUTON'S TYROSINE KINASE". . . Retrieved 2016/01/25.
• 2、 -. "CARBINOL DERIVATIVES HAVING HETEROCYCLIC LINKER". Page/Page column 23. . Retrieved 2010/12/29.