3-PHENOXYPHENETHYLAMINE

Base Information

• Chemical Name: 3-PHENOXYPHENETHYLAMINE
• CAS No.: 51061-22-4
• Molecular Formula: C15H17 N O
• Molecular Weight: 227.306
• Hs Code.: 2922199090
• Mol file: 51061-22-4.mol

Synonyms:2-(3-Benzyloxyphenyl)ethylamine;2-[3-(Benzyloxy)phenyl]ethanamine; 3-(Benzyloxy)-b-phenethylamine; 3-(Benzyloxy)phenethylamine;3-(Benzyloxy)phenylethylamine

Chemical Property of 3-PHENOXYPHENETHYLAMINE

Chemical Property:

• Vapor Pressure: 1.13E-05mmHg at 25°C
• Boiling Point: 370.1°Cat760mmHg
• PKA: 9.84±0.10(Predicted)
• Flash Point: 179.3°C
• PSA: 35.25000
• Density: 1.079g/cm³
• LogP: 4.26910

Purity/Quality:

97% ^*data from raw suppliers

2-(3-BENZYLOXY-PHENYL)-ETHYLAMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-PHENOXYPHENETHYLAMINE

There total 14 articles about 3-PHENOXYPHENETHYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1-(benzyloxy)-3-(2-nitrovinyl)benzene (24550-32-1) → 2-(3-benzyloxyphenyl)ethylamine (51061-22-4)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; dichloromethane; for 0.5h; Ambient temperature;

DOI:10.1021/jm00376a017

Reference yield: 71.0%

2-(3-benzyloxyphenyl)acetonitrile (20967-96-8) → 2-(3-benzyloxyphenyl)ethylamine (51061-22-4)

Guidance literature:

With borane-THF; In tetrahydrofuran; for 18h; Reflux;

DOI:10.1016/j.bmcl.2010.03.097

Reference yield: 51.0%

Na2SO4.10H2O + 2-(3-benzyloxyphenyl)acetonitrile (20967-96-8) → 2-(3-benzyloxyphenyl)ethylamine (51061-22-4)

Guidance literature:

With LiAlH₄; In tetrahydrofuran; dichloromethane;

upstream raw materials:

1-(benzyloxy)-3-(2-nitrovinyl)benzene

1-(benzyloxy)-3-[(E)-2-nitroethenyl]benzene

3-Benzyloxybenzaldehyde

benzyl chloride

Downstream raw materials:

N-(3-benzyloxyphenethyl)-2-(6-bromo-3,4-dimethoxyphenyl)acetamide

m-tyramine

N-[2-(3-Benzyloxy-phenyl)-ethyl]-3-(4-hydroxy-phenyl)-propionamide

N-[2-(3-Benzyloxy-phenyl)-ethyl]-3-(3-hydroxy-phenyl)-propionamide