Technology Process of 5-tert-butyl-2-fluoro-1,3-dimethylbenzene
There total 6 articles about 5-tert-butyl-2-fluoro-1,3-dimethylbenzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrafluoroboric acid; sodium nitrite;
In
tetrahydrofuran; water;
- Guidance literature:
-
With
2-chloro-[1,10]phenanthroline; {Pd(2,2':6',2''-terpyridine)(acetonitrile)}(BF4)2; N-fluorobis(benzenesulfon)imide;
In
acetonitrile;
at 25 ℃;
for 24h;
Reagent/catalyst;
Temperature;
Overall yield = 118 mg;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: AlCl3-MeNO2
2: 75 percent / acetic anhydride, nitric acid, acetic acid / 25 °C
3: 89 percent / Fe-HCl / H2O; ethanol / 28 h / Heating
4: 48 percent / HBF4, NaNO2 / tetrahydrofuran; H2O
With
tetrafluoroboric acid; nitric acid; acetic anhydride; acetic acid; sodium nitrite;
aluminium trichloride; nitromethane;
In
tetrahydrofuran; ethanol; water;
