C₁₁H₁₁FO₃

Base Information

• Chemical Name: C₁₁H₁₁FO₃
• CAS No.: 1235454-61-1
• Molecular Formula: C₁₁H₁₁FO₃
• Molecular Weight: 210.205
• Mol file: 1235454-61-1.mol

Synonyms:C₁₁H₁₁FO₃

Chemical Property of C₁₁H₁₁FO₃

Chemical Property:

Purity/Quality:

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Technology Process of C₁₁H₁₁FO₃

There total 1 articles about C₁₁H₁₁FO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Isopropenyl acetate (108-22-5) + 1-(2-fluoro-4-methoxyphenyl)-1-ethanone (74457-86-6) → C11H11FO3 (1235454-61-1)

Guidance literature:

With toluene-4-sulfonic acid; at 120 ℃; for 24h; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.orglett.0c04021

Reference yield: 76.0%

C11H11FO3 (1235454-61-1) + (Difluoromethyl)triphenylphosphonium bromide (58310-28-4) → 3,3-difluoro-1-(2-fluoro-4-methoxyphenyl)propan-1-one

Guidance literature:

With fac-tris(2-phenylpyridinato-N,C₂')iridium(III); In 1-methyl-pyrrolidin-2-one; at 20 ℃; for 36h; Inert atmosphere; Schlenk technique; Sealed tube; Irradiation;

DOI:10.1021/acs.orglett.0c04021

Reference yield: 72.0%

triphenylboroxine (3262-89-3) + C11H11FO3 (1235454-61-1) → 2-fluoro-4-methoxy-1-(1-phenyl-vinyl)-benzene (24890-55-9)

Guidance literature:

With potassium phosphate; bis(tricyclohexylphosphine)nickel(II) dichloride; water; In 1,4-dioxane; toluene; at 110 ℃; for 20h; Inert atmosphere;

DOI:10.1002/chem.200902785

upstream raw materials:

Isopropenyl acetate

1-(2-fluoro-4-methoxyphenyl)-1-ethanone

Downstream raw materials:

2-fluoro-4-methoxy-1-(1-phenyl-vinyl)-benzene

Refernces