(S)-ethyl 2-(tert-butoxycarbonyl(methoxymethyl)amino)-3-(4-ethoxyphenyl)propanoate

Base Information

Chemical Name:(S)-ethyl 2-(tert-butoxycarbonyl(methoxymethyl)amino)-3-(4-ethoxyphenyl)propanoate
CAS No.:1376605-50-3
Molecular Formula:C₂₀H₃₁NO₆
Molecular Weight:381.469
Hs Code.:

Synonyms:(S)-ethyl 2-(tert-butoxycarbonyl(methoxymethyl)amino)-3-(4-ethoxyphenyl)propanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-ethyl 2-(tert-butoxycarbonyl(methoxymethyl)amino)-3-(4-ethoxyphenyl)propanoate

Chemical Property:

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Technology Process of (S)-ethyl 2-(tert-butoxycarbonyl(methoxymethyl)amino)-3-(4-ethoxyphenyl)propanoate

There total 1 articles about (S)-ethyl 2-(tert-butoxycarbonyl(methoxymethyl)amino)-3-(4-ethoxyphenyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 101998-39-4
C₁₈H₂₇NO₅

: 107-30-2
chloromethyl methyl ether

: 1376605-50-3
(S)-ethyl 2-(tert-butoxycarbonyl(methoxymethyl)amino)-3-(4-ethoxyphenyl)propanoate

Guidance literature:: With potassium hexamethylsilazane; In tetrahydrofuran; at -78 ℃; for 17.5h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1039/c2cc31447a

Reference yield:

: 1376605-50-3
(S)-ethyl 2-(tert-butoxycarbonyl(methoxymethyl)amino)-3-(4-ethoxyphenyl)propanoate

: 100-52-7
benzaldehyde

: ethyl 4-(4-ethoxybenzyl)-3-(methoxymethyl)-2-oxo-5-phenyloxazolidine-4-carboxylate

: 1376605-51-4
ethyl 4-(4-ethoxybenzyl)-3-(methoxymethyl)-2-oxo-5-phenyloxazolidine-4-carboxylate

Guidance literature:: With potassium hexamethylsilazane; In tert-butyl methyl ether; toluene; at -40 ℃; for 6h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1039/c2cc31447a