1-(Iodomethyl)naphthalene

Base Information

• Chemical Name: 1-(Iodomethyl)naphthalene
• CAS No.: 24471-54-3
• Molecular Formula: C11H9I
• Molecular Weight: 268.097
• Hs Code.: 2903999090
• DSSTox Substance ID: DTXSID20376698
• Nikkaji Number: J813.888E
• Wikidata: Q82165591
• Mol file: 24471-54-3.mol

Synonyms:1-(iodomethyl)naphthalene;24471-54-3;iodomethylnaphthalene;SCHEMBL3196492;DTXSID20376698;1-(IODOMETHYL)-NAPHTHALENE;NAPHTHALENE,1-(IODOMETHYL)-;AKOS014117145;FT-0707938

Chemical Property of 1-(Iodomethyl)naphthalene

Chemical Property:

• Vapor Pressure: 0.000291mmHg at 25°C
• Refractive Index: 1.709
• Boiling Point: 331.9 °C at 760 mmHg
• Flash Point: 165.7 °C
• PSA: 0.00000
• Density: 1.689 g/cm³
• LogP: 3.77480
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 267.97490
• Heavy Atom Count: 12
• Complexity: 144

Purity/Quality:

98%Min ^*data from raw suppliers

1-(IODOMETHYL)-NAPHTHALENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC=C2CI

Technology Process of 1-(Iodomethyl)naphthalene

There total 2 articles about 1-(Iodomethyl)naphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-naphthalene methanol (4780-79-4) → (naphtalen-1-yl)methyl iodide (24471-54-3) + 1-Methylnaphthalene (90-12-0,34475-76-8)

Guidance literature:

With phosphorus; hydrogen iodide; In water; toluene; at 80 ℃; for 2h; Inert atmosphere;

DOI:10.3762/bjoc.8.36

Reference yield:

1-phenyl-pent-4-yn-2-ol → (naphtalen-1-yl)methyl iodide (24471-54-3) + 4-(iodomethylene)-1,2,3,4-tetrahydronaphthalen-2-ol + 1-Chloromethylnaphthalene (86-52-2)

Guidance literature:

With Iodine monochloride; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.tetlet.2016.03.047

Reference yield: 92.0%

(naphtalen-1-yl)methyl iodide (24471-54-3) → 1-naphthaldehyde (66-77-3)

Guidance literature:

With 1?dodecyl?3?methylimidazolium iron chloride; periodic acid; at 50 ℃; for 4h; Reagent/catalyst; Green chemistry;

DOI:10.1007/s11696-018-0657-6

upstream raw materials:

1-naphthalene methanol

Downstream raw materials:

1-(methoxymethyl)naphthalene

1-naphthaldehyde

3-(α-naphthyl)-2-(phenylthio)-2-(α-naphthylmethyl)cyclopentanone

1-Methylnaphthalene

Refernces

• 1、 Dobmeier, Michael,Herrmann, Josef M.,Lenoir, Dieter,Koenig, Burkhard. "Reduction of benzylic alcohols and α-hydroxycarbonyl compounds by hydriodic acid in a biphasic reaction medium". supporting information; experimental part. p. 330 - 336. Retrieved 2012/05/20.