Technology Process of C15H14BrN
There total 2 articles about C15H14BrN which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
potassium carbonate;
tetrakis(triphenylphosphine) palladium(0);
In
methanol;
at 60 ℃;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: Iodine monochloride / acetic acid / 20 °C
2: potassium carbonate / tetrakis(triphenylphosphine) palladium(0) / methanol / 60 °C / Inert atmosphere
With
Iodine monochloride; potassium carbonate;
tetrakis(triphenylphosphine) palladium(0);
In
methanol; acetic acid;
2: Suzuki Coupling;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium nitrite; hydrogen bromide / water / 0.5 h / -15 - -10 °C
1.2: 12 h / -15 - 20 °C
2.1: bis-triphenylphosphine-palladium(II) chloride / 1,4-dioxane / 16 h / 90 °C / Inert atmosphere
2.2: 2 h / 20 °C / cooling with ice
With
hydrogen bromide; sodium nitrite;
bis-triphenylphosphine-palladium(II) chloride;
In
1,4-dioxane; water;