N-[4-amino-3-benzoylphenyl]-N^α-tert-butyloxycarbonyl-S-tritylcysteinamide

Base Information

Chemical Name:N-[4-amino-3-benzoylphenyl]-N^α-tert-butyloxycarbonyl-S-tritylcysteinamide
CAS No.:366456-89-5
Molecular Formula:C₄₀H₃₉N₃O₄S
Molecular Weight:657.833
Hs Code.:

N-[4-amino-3-benzoylphenyl]-N<sup>α</sup>-tert-butyloxycarbonyl-S-tritylcysteinamide

Synonyms:N-[4-amino-3-benzoylphenyl]-N^α-tert-butyloxycarbonyl-S-tritylcysteinamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[4-amino-3-benzoylphenyl]-N^α-tert-butyloxycarbonyl-S-tritylcysteinamide

Chemical Property:

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Technology Process of N-[4-amino-3-benzoylphenyl]-N^α-tert-butyloxycarbonyl-S-tritylcysteinamide

There total 6 articles about N-[4-amino-3-benzoylphenyl]-N^α-tert-butyloxycarbonyl-S-tritylcysteinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 366456-88-4
N-[3-benzoyl-4-(trifluoroacetylamino)phenyl]-N^α-tert-butyloxycarbonyl-S-tritylcysteinamide

: 366456-89-5
N-[4-amino-3-benzoylphenyl]-N^α-tert-butyloxycarbonyl-S-tritylcysteinamide

Guidance literature:: With potassium carbonate; In 1,4-dioxane; for 3h; Heating;
DOI:10.1021/jm010872r

Reference yield:

: 21947-98-8,87494-13-1
N-tert-butyloxycarbonyl-S-trityl-L-cysteine

: 366456-89-5
N-[4-amino-3-benzoylphenyl]-N^α-tert-butyloxycarbonyl-S-tritylcysteinamide

Guidance literature:: Multi-step reaction with 3 steps

1: N-methylmorpholine / dimethylformamide / 0.08 h / -15 °C

2: dimethylformamide / -15 - 20 °C

3: 88 percent / aq. K₂CO₃ / dioxane / 3 h / Heating

With 4-methyl-morpholine; potassium carbonate; In 1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1021/jm010872r

Reference yield:

: Boc-Cys(Trt)-OH

: 366456-89-5
N-[4-amino-3-benzoylphenyl]-N^α-tert-butyloxycarbonyl-S-tritylcysteinamide

Guidance literature:: Multi-step reaction with 2 steps

1: dimethylformamide / -15 - 20 °C

2: 88 percent / aq. K₂CO₃ / dioxane / 3 h / Heating

With potassium carbonate; In 1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1021/jm010872r